Association of elevated lipoprotein (a) levels and coronary heart disease in NIDDM patients. Relationship with apolipoprotein (a) phenotypes

J Ruiz, J Thillet, T Huby, RW James, D Erlich, P Flandre… - Diabetologia, 1994 - Springer
Non-insulin-dependent diabetes mellitus (NIDDM) is a strong and independent risk factor for
coronary heart disease. We assessed the potential relationship between plasma Lp (a) …

Increased serum lipoprotein (a) concentrations and low molecular weight phenotypes of apolipoprotein (a) are associated with symptomatic peripheral arterial disease

B Dieplinger, A Lingenhel, N Baumgartner… - Clinical …, 2007 - academic.oup.com
Background: Increased concentrations of lipoprotein (a)[Lp (a)] have been considered a
genetically determined risk factor for coronary artery and cerebrovascular disease. Only 2 …

Low lipoprotein (a) levels and risk of disease in a large, contemporary, general population study

A Langsted, BG Nordestgaard… - European heart …, 2021 - academic.oup.com
Aims With the current focus on lipoprotein (a) as a likely causal risk factor for cardiovascular
disease and new drugs potentially on the market to lower lipoprotein (a) levels, the safety of …

[HTML][HTML] Lipoprotein (a) levels, apo (a) isoform size, and coronary heart disease risk in the Framingham Offspring Study

S Lamon-Fava, SM Marcovina, JJ Albers… - Journal of lipid …, 2011 - ASBMB
The aim of this study was to assess the independent contributions of plasma levels of
lipoprotein (a)(Lp (a)), Lp (a) cholesterol, and of apo (a) isoform size to prospective coronary …

Lipoprotein (a) and cardiovascular and valvular diseases: a genetic epidemiological perspective

BJ Arsenault, PR Kamstrup - Atherosclerosis, 2022 - Elsevier
Rates of atherosclerotic cardiovascular diseases (CVD) in the Western world have
spectacularly decreased over the past 50 years. However, a substantial proportion of high …

Apolipoprotein (a) genetic polymorphism and serum lipoprotein (a) concentration in patients with peripheral vascular disease

J Pedro-Botet, M Senti, T Auguet, X Nogués… - Atherosclerosis, 1993 - Elsevier
Abstract Serum lipoprotein (a)(Lp (a)) levels were measured in 89 men with peripheral
vascular disease (PVD) and 129 (100 male and 29 woman) healthy controls. Apolipoprotein …

[HTML][HTML] A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms [S]

S Mack, S Coassin, R Rueedi, NA Yousri… - Journal of lipid …, 2017 - ASBMB
High lipoprotein (a)[Lp (a)] concentrations are an independent risk factor for cardiovascular
outcomes. Concentrations are strongly influenced by apo (a) kringle IV repeat isoforms. We …

Apo (a) isoforms predict risk for coronary heart disease. A study in six populations.

C Sandholzer, N Saha, JD Kark, A Rees… - … and thrombosis: a …, 1992 - Am Heart Assoc
Elevated concentrations of lipoprotein (a)(Lp [a]) in plasma are associated with premature
coronary heart disease (CHD). Lp (a) levels are largely determined by alleles at the …

Three single-nucleotide polymorphisms in LPA account for most of the increase in lipoprotein (a) level elevation in African Americans compared with European …

JP Chretien, J Coresh, Y Berthier-Schaad… - Journal of medical …, 2006 - jmg.bmj.com
Background: The extent which universally common or population-specific alleles can
explain between-population variations in phenotypes is unknown. The heritable coronary …

Lipoprotein (a): resurrected by genetics

F Kronenberg, G Utermann - Journal of internal medicine, 2013 - Wiley Online Library
Plasma lipoprotein (a)[L p (a)] is a quantitative genetic trait with a very broad and skewed
distribution, which is largely controlled by genetic variants at the LPA locus on chromosome …