MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics

A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …

[HTML][HTML] Role of microRNAs in glioblastoma

M Chen, Z Medarova, A Moore - Oncotarget, 2021 - ncbi.nlm.nih.gov
Glioblastoma is the most common and aggressive primary human brain cancer. MicroRNAs
(miRNAs) are a set of small endogenous non-coding RNA molecules which play critical …

miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay

SS Elshaer, AI Abulsoud, D Fathi… - … -Research and Practice, 2023 - Elsevier
High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …

MicroRNAs in glioblastoma pathogenesis and therapy: A comprehensive review

BK Ahir, H Ozer, HH Engelhard, SS Lakka - Critical Reviews in Oncology …, 2017 - Elsevier
Glioblastoma (GBM), also known as grade IV astrocytoma, is the most aggressive primary
intracranial tumor of the adult brain. MicroRNAs (miRNAs), a class of small non-coding RNA …

Therapeutically significant microRNAs in primary and metastatic brain malignancies

AA Balachandran, LM Larcher, S Chen, RN Veedu - Cancers, 2020 - mdpi.com
Simple Summary The overall survival of brain cancer patients remains grim, with
conventional therapies such as chemotherapy and radiotherapy only providing marginal …

MicroRNA-based drugs for brain tumors

S Anthiya, A Griveau, C Loussouarn, P Baril, M Garnett… - Trends in cancer, 2018 - cell.com
MicroRNAs (miRNAs) are key regulatory elements encoded by the genome. A single miRNA
can downregulate the expression of multiple genes involved in diverse functions. Because …

MicroRNA in human glioma

M Li, J Li, L Liu, W Li, Y Yang, J Yuan - Cancers, 2013 - mdpi.com
Glioma represents a serious health problem worldwide. Despite advances in surgery,
radiotherapy, chemotherapy, and targeting therapy, the disease remains one of the most …

Current progress on understanding microRNAs in glioblastoma multiforme

M Karsy, E Arslan, F Moy - Genes & cancer, 2012 - journals.sagepub.com
Glioblastoma multiforme (GBM) is an aggressive grade IV astrocytoma with a 1-year median
survival rate despite current treatment modalities. A thorough understanding of the vast …

Role of microRNAs in gliomagenesis: targeting miRNAs in glioblastoma multiforme therapy

A Nikaki, C Piperi, AG Papavassiliou - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Gliomas consist of a very heterogeneous group of malignant tumors,
accounting for 50–60% of primary brain tumors. Despite all the efforts of cytoreductive …

A systematic review of microRNA in glioblastoma multiforme: micro-modulators in the mesenchymal mode of migration and invasion

HG Møller, AP Rasmussen, HH Andersen… - Molecular …, 2013 - Springer
Glioblastoma multiforme (GBM) is an incurable form of brain cancer with a very poor
prognosis. Because of its highly invasive nature, it is impossible to remove all tumor cells …