The Fyx phenotype is associated with a missense mutation in the Fyb allele predicting Arg89Cys in the Duffy glycoprotein

ML Olsson, JS Smythe, C Hansson… - British journal of …, 1998 - Wiley Online Library
The molecular basis of the three major alleles (Fya/Fyb/Fy) of the Duffy (FY) blood group
system has recently been established but the Fyx phenotype associated with weak …

[HTML][HTML] Molecular basis of the Duffy blood group system

G Höher, M Fiegenbaum, S Almeida - Blood Transfusion, 2018 - ncbi.nlm.nih.gov
ACKR1, located on chromosome 1q23. 2, is the gene that encodes a glycoprotein
expressing the Duffy blood group antigens. This gene is transcribed in two mRNA variants …

[PDF][PDF] Fy^ x is associated with two missense point mutations in its gene and can be detected by PCR-SSP

C Gassner, RL Kraus, T Dovc… - …, 2000 - scholar.archive.org
FY* B polymorphism is caused by a missense point mutation at NT 129 of the Duffy gene,
changing Gly42 in Fya to Asp42 in Fyb. 18–20, 22 In Fy (a–b–) people, most of whom are …

DNA analysis of Duffy genes in American blacks

JM Moulds, S Hayes, TD Wells - Vox sanguinis, 1998 - karger.com
Background: Because limited studies have shown that the Duffy genotype is not accurately
reflected by the erythrocyte phenotype, we used PCR-RFLP to determine the true FY1 and …

New genotypes in Fy(a− b−) individuals: nonsense mutations (Trp to stop) in the coding sequence of either FY A or FY B

Rios, Chaudhuri, Mallinson, Sausais… - British journal of …, 2000 - Wiley Online Library
Duffy blood group antigens are carried on a glycoprotein that is predicted to pass through
the erythrocyte membrane seven times and is a promiscuous chemokine receptor. The Fy …

Duffy blood group phenotype–genotype correlations using high‐resolution melting analysis PCR and microarray reveal complex cases including a new null FY*A …

GH Lopez, J Morrison, JA Condon, B Wilson… - Vox …, 2015 - Wiley Online Library
Background and objectives Duffy blood group phenotypes can be predicted by genotyping
for single nucleotide polymorphisms (SNP s) responsible for the Fya/Fyb polymorphism, for …

Present status of the Duffy blood group system: articles reviewed

WL Marsh, PJ Schmidt - CRC critical reviews in clinical laboratory …, 1975 - Taylor & Francis
The Duffy blood group has five antigenic specificities, Fya, Fyb, Fy3, Fy4, and Fy5, that are
part of, or related to, the system. The first four antigens are under the genetic control of a …

A clinically applicable method for determining the three major alleles at the Duffy (FY) blood group locus using polymerase chain reaction with allele‐specific primers

ML Olsson, C Hansson, ND Avent, IE Akesson… - …, 1998 - Wiley Online Library
BACKGROUND: The clinically significant antigens of the Duffy (Fy [FY]) blood group system
are expressed on the red cell form of the FY glycoprotein, a promiscuous chemokine …

Arg89Cys Substitution Results in Very Low Membrane Expression of the Duffy Antigen/Receptor for Chemokines in Fyx Individuals

C Tournamille, C Le Van Kim, P Gane… - Blood, The Journal …, 1998 - ashpublications.org
The Duffy (FY) blood group antigens are carried by the DARC glycoprotein, a widely
expressed chemokine receptor. The molecular basis of the Fya/Fyb and Fy (ab-) …

A novel FY*A allele with the 265T and 298A SNPs formerly associated exclusively with the FY*B allele and weak Fyb antigen expression: implication for genotyping …

GH Lopez, JA Condon, B Wilson, JR Martin… - Vox …, 2015 - Wiley Online Library
Background and Objectives An Australian Caucasian blood donor consistently presented a
serology profile for the Duffy blood group as Fy (a+ b+) with Fya antigen expression weaker …