Treatment of Wound Infections in a Mouse Model Using Zn2+-Releasing Phage Bound to Gold Nanorods

H Peng, D Rossetto, SS Mansy, MC Jordan, KP Roos… - ACS …, 2022 - ACS Publications
Infections caused by drug-resistant bacteria, particularly Gram-negative organisms, are
increasingly difficult to treat using antibiotics. A potential alternative is “phage therapy”, in …

Controlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phages

H Peng, RE Borg, LP Dow… - Proceedings of the …, 2020 - National Acad Sciences
The use of bacteriophages (phages) for antibacterial therapy is under increasing
consideration to treat antimicrobial-resistant infections. Phages have evolved multiple …

Pharmaceutical Intermediate-Modified Gold Nanoparticles: Against Multidrug-Resistant Bacteria and Wound-Healing Application via an Electrospun Scaffold

X Yang, J Yang, L Wang, B Ran, Y Jia, L Zhang… - Acs Nano, 2017 - ACS Publications
Remedying a multidrug-resistant (MDR) bacteria wound infection is a major challenge due
to the inability of conventional antibiotics to treat such infections against MDR bacteria. Thus …

Microenvironment‐Activated Nanozyme‐Armed Bacteriophages Efficiently Combat Bacterial Infection

L Jin, F Cao, Y Gao, C Zhang, Z Qian… - Advanced …, 2023 - Wiley Online Library
Bacterial infection is one of the greatest challenges to public health, requiring new
therapeutic methods. Herein, an innovative nanozyme‐armed phage (phage@ palladium …

Indole derivative-capped gold nanoparticles as an effective bactericide in vivo

X Zhao, Y Jia, J Li, R Dong, J Zhang, C Ma… - … applied materials & …, 2018 - ACS Publications
We synthesize indole derivative-capped gold nanoparticles (Au_IDs) via a straightforward
route to fight multidrug-resistant (MDR) bacteria. When gold nanoparticles are modified with …

Carbohydrate-Coated Gold–Silver Nanoparticles for Efficient Elimination of Multidrug Resistant Bacteria and in Vivo Wound Healing

S Kumar, RK Majhi, A Singh, M Mishra… - … applied materials & …, 2019 - ACS Publications
Multidrug resistant (MDR) bacteria have emerged as a major clinical challenge. The
unavailability of effective antibiotics has necessitated the use of emerging nanoparticles as …

Intelligent nanoparticle-based dressings for bacterial wound infections

L Jiang, SCJ Loo - ACS Applied Bio Materials, 2020 - ACS Publications
Conventional wound dressing materials containing free antibiotics for bacterial wound
infections are presented with several limitations, that is, lack of controlled and triggered …

[HTML][HTML] Nanoparticle-based devices in the control of antibiotic resistant bacteria

MF Gómez-Núñez, M Castillo-López… - Frontiers in …, 2020 - frontiersin.org
Antimicrobial resistance (AR) is one of the most important public health challenges
worldwide as it represents a serious complication that is able to increase the mortality …

Multivalent aminosaccharide-based gold nanoparticles as narrow-spectrum antibiotics in vivo

X Yang, Q Wei, H Shao, X Jiang - ACS applied materials & …, 2019 - ACS Publications
Bacterial infection, especially multidrug-resistant (MDR) bacteria-induced wound infection, is
an enormous challenge and is the result of the inability of traditional antibiotics to combat …

Inhibition of bacteria in vitro and in vivo by self-assembled DNA-silver nanocluster structures

S Liu, Q Yan, S Cao, L Wang, SH Luo… - ACS Applied Materials & …, 2022 - ACS Publications
Antimicrobial nanomaterials hold great promise for bacteria-infected wound healing.
However, it remains a challenge to balance antimicrobial efficacy and biocompatibility for …