Mutation and subsequent recombination events create genetic diversity, which is subjected
to natural selection. Bacterial mismatch repair (MMR) deficient mutants, exhibiting high …

The Salmonella typhimurium and Escherichia coli MutS protein is one of several methyl‐
directed mismatch repair proteins that act together to correct replication errors. MutS is …

The Escherichia coli DNA Mismatch Repair (MMR) protein MutS exist as dimers and
tetramers in solution, and the identification of its functional oligomeric state has been matter …

The process of mismatch repair was first postulated to explain the results of experiments on
genetic recombination and bacterial mutagenesis. Mismatch repair has long been known to …

High-resolution crystal structures have recently been solved for the mismatch binding
protein MutS of Escherichia coli and its Thermus aquaticus homologue; they show how …

The mutation rate of an organism is influenced by the interaction of evolutionary forces such
as natural selection and genetic drift. However, the mutation spectrum (ie, the frequency …

Bacterial MutS proteins are subdivided into two families, MutS1 and MutS2. MutS1 family
members recognize DNA replication errors during their participation in the well …

The products of the mutD and mutL genes of Escherichia coli are involved in proofreading
by DNA polymerase III and DNA adenine MTase (Dam)-dependent mismatch repair …

The Escherichia coli dnaQ49 mutator allele maps at the dnaQ locus, the structural gene for
the epsilon subunit of the DNA polymerase III holoenzyme. Epsilon, when bound to the …

Publisher Summary There are several scientific reviews available that deal with the
multitude of molecular processes involved in repairing various DNA lesions. The chapter …