Cell-competitive interactions are widespread in nature and determine the outcome of a vast
variety of biological processes. A particular class of competitive interactions takes place …

In multicellular organisms, incidentally emerging suboptimal cells are removed to maintain
homeostasis of tissues. The unfavorable cells are excluded by a process termed cell …

From fertilization until the onset of gastrulation the early mammalian embryo undergoes a
dramatic series of changes that converts a single fertilized cell into a remarkably complex …

The growth and survival of cells within tissues can be affected by 'cell competition'between
different cell clones. This phenomenon was initially recognized between wild-type cells and …

The eukaryotic cell is morphologically and functionally organized as an interconnected
network of organelles that responds to stress and aging. Organelles communicate via …

Mitochondrial and cytosolic proteostasis are of central relevance for cellular stress
resistance and organismal health. Recently, a number of individual cellular programs were …

Eukaryotic cells attempt to maintain an optimal size, resulting in size homeostasis. While
cellular content scales isometrically with cell size, allometric laws indicate that metabolism …

Mitochondria are ancient organelles evolved from bacteria. Over the course of evolution, the
behavior of mitochondria inside eukaryotic cells has changed dramatically, and the …

Mitochondria are essential to cell homeostasis, and alterations in mitochondrial distribution,
segregation, and turnover have been linked to complex pathologies such as …

Mitochondria contain two membranes, the outer and inner membrane. The outer membrane
fulfills crucial functions for the communication of mitochondria with the cellular environment …