Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation
N Ferreira, KL Perks, G Rossetti, DL Rudler… - The EMBO …, 2019 - embopress.org
Translation fidelity is crucial for prokaryotes and eukaryotic nuclear‐encoded proteins;
however, little is known about the role of mistranslation in mitochondria and its potential …
however, little is known about the role of mistranslation in mitochondria and its potential …
[HTML][HTML] Cell competition: A historical perspective
G Morata - Developmental Biology, 2021 - Elsevier
Cell competition is a homeostatic process designed to remove from animal tissues viable
cells that are unfit, abnormal or malignant and that may compromise the general fitness or …
cells that are unfit, abnormal or malignant and that may compromise the general fitness or …
Survival of the fittest: essential roles of cell competition in development, aging, and cancer
Multicellular organisms evolved to resolve conflicts between individual cells, protecting the
internal organization of the individual. This is illustrated by cell competition, a process that …
internal organization of the individual. This is illustrated by cell competition, a process that …
Cell competition: Emerging mechanisms to eliminate neighbors
R Nagata, T Igaki - Development, growth & differentiation, 2018 - Wiley Online Library
Cell competition is a context‐dependent cell elimination through short‐range cell–cell
interaction, in which cells with higher fitness eliminate neighboring less‐fit or oncogenic …
interaction, in which cells with higher fitness eliminate neighboring less‐fit or oncogenic …
Proteotoxic stress is a driver of the loser status and cell competition
ME Baumgartner, MP Dinan, PF Langton… - Nature Cell …, 2021 - nature.com
Cell competition allows winner cells to eliminate less fit loser cells in tissues. In Minute cell
competition, cells with a heterozygous mutation in ribosome genes, such as RpS3+/− cells …
competition, cells with a heterozygous mutation in ribosome genes, such as RpS3+/− cells …
The competitive nature of cells
The possibility that cells of multicellular organisms may compete with one another has been
postulated several times. It was experimentally confirmed in Drosophila, probably for the first …
postulated several times. It was experimentally confirmed in Drosophila, probably for the first …
[HTML][HTML] Mitochondria lead the way: mitochondrial dynamics and function in cellular movements in development and disease
S Madan, B Uttekar, S Chowdhary… - Frontiers in Cell and …, 2022 - frontiersin.org
The dynamics, distribution and activity of subcellular organelles are integral to regulating
cell shape changes during various physiological processes such as epithelial cell formation …
cell shape changes during various physiological processes such as epithelial cell formation …
Picking winners and losers: cell competition in tissue development and homeostasis
W Kim, R Jain - Trends in Genetics, 2020 - cell.com
Viable cells with reduced fitness are often eliminated by neighboring cells with greater
fitness. This phenomenon, called cell competition, is an important mechanism for …
fitness. This phenomenon, called cell competition, is an important mechanism for …
Why do cells need oxygen? Insights from mitochondrial composition and function
Mitochondrial membrane‐embedded redox proteins are classically perceived as
deterministic “electron transport chain”(ETC) arrays cum proton pumps; and oxygen is seen …
deterministic “electron transport chain”(ETC) arrays cum proton pumps; and oxygen is seen …
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate
M Diaz-Cuadros - Current Opinion in Genetics & Development, 2024 - Elsevier
Highlights•The speed of gene expression steps correlates with the rate of embryonic
development.•Mitochondrial metabolism may give rise to species-specific gene expression …
development.•Mitochondrial metabolism may give rise to species-specific gene expression …