Why do cells need oxygen? Insights from mitochondrial composition and function

KM Manoj, DA Gideon, L Jaeken - Cell Biology International, 2022 - Wiley Online Library
Mitochondrial membrane‐embedded redox proteins are classically perceived as
deterministic “electron transport chain”(ETC) arrays cum proton pumps; and oxygen is seen …

Mechanistic aspects of mammalian cell size control

K Yamamoto, TW Mak - Development, growth & differentiation, 2017 - Wiley Online Library
Size distribution in a group of differentiated cells often falls into a constant range. However,
in vitro and in vivo studies have shown that cells can temporarily change their size in …

Mitochondrial dynamics in stem cells and differentiation

BJ Seo, SH Yoon, JT Do - International journal of molecular sciences, 2018 - mdpi.com
Mitochondria are highly dynamic organelles that continuously change their shape. Their
main function is adenosine triphosphate (ATP) production; however, they are additionally …

Cytosolic quality control of mitochondrial protein precursors—the early stages of the organelle biogenesis

AM Lenkiewicz, M Krakowczyk… - International Journal of …, 2021 - mdpi.com
With few exceptions, proteins that constitute the proteome of mitochondria originate outside
of this organelle in precursor forms. Such protein precursors follow dedicated transportation …

Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate

M Diaz-Cuadros - Current Opinion in Genetics & Development, 2024 - Elsevier
Highlights•The speed of gene expression steps correlates with the rate of embryonic
development.•Mitochondrial metabolism may give rise to species-specific gene expression …

Linking mitochondrial dynamics to mitochondrial protein quality control

S Haroon, M Vermulst - Current opinion in genetics & development, 2016 - Elsevier
Over the last decade, countless discoveries have been made that have expanded our
knowledge of mitochondrial biology, and more often than not, these discoveries provided …

Cell competition, apoptosis and tumour development

G Morata, L Ballesteros-Arias - 2015 - digital.csic.es
© 2015 UBC Press. The phenomenon of cell competition is an interactive process originally
discovered in the imaginal discs of Drosophila; it is a developmental mechanism that …

Identification of transcriptional and metabolic programs related to mammalian cell size

TP Miettinen, HKJ Pessa, MJ Caldez, T Fuhrer, MK Diril… - Current Biology, 2014 - cell.com
Background Regulation of cell size requires coordination of growth and proliferation.
Conditional loss of cyclin-dependent kinase 1 in mice permits hepatocyte growth without cell …

Inheritance of the fittest mitochondria in yeast

JD Vevea, TC Swayne, IR Boldogh, LA Pon - Trends in cell biology, 2014 - cell.com
Eukaryotic cells compartmentalize their biochemical processes within organelles, which
have specific functions that must be maintained for overall cellular health. As the site of …

Mitochondria and the non‐genetic origins of cell‐to‐cell variability: more is different

R Guantes, J Díaz‐Colunga, FJ Iborra - Bioessays, 2016 - Wiley Online Library
Gene expression activity is heterogeneous in a population of isogenic cells. Identifying the
molecular basis of this variability will improve our understanding of phenomena like tumor …