Cell competition is a cell fitness-sensing mechanism conserved from insects to mammals
that eliminates those cells that, although viable, are less fit than their neighbors. An …

Cells adopt a size that is optimal for their function, and pushing them beyond this limit can
cause cell aging and death by senescence or reduce proliferative potential. However, by …

Mitochondrial efficiency directs cell fate | Nature Cell Biology Skip to main content Thank you for
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The maintenance of cell size homeostasis has been studied for years in different cellular
systems. With the focus on 'what regulates cell size', the question 'why cell size needs to be …

Mitochondria are considered highly plastic organelles. This plasticity enables the
mitochondria to undergo morphological and functional changes in response to cellular …

The coordination of nuclear and mitochondrial genomes plays a pivotal role in maintenance
of mitochondrial biogenesis and functionality during stress and aging. Environmental and …

Mitochondrial homeostasis is maintained by several quality control mechanisms, including
an unfolded protein response that in turn elicits a transcriptional response. In a recent issue …

Mitochondrial functions are essential for life, critical for development, maintenance of stem
cells, adaptation to physiological changes, responses to stress, and aging. The complexity of …

Mitochondria are essential organelles that are responsible for cellular energy production
and cell death in response to various stimuli. Although C-terminal binding protein (CtBP) …

A protein's function is intimately linked to its correct subcellular location, yet the machinery
required for protein synthesis is predominately cytosolic. How proteins are trafficked through …