Background Clostridium botulinum C2 toxin and Clostridium perfringens iota toxin are binary
exotoxins, which ADP-ribosylate actin in the cytosol of mammalian cells and thereby destroy …

ADP-ribosyltransferase C3 is an exoenzyme produced by several strains of Clostridium
botulinum. It was serendipitously detected during screening for high producer strains of C …

Botulinum toxin type A (BoNT/A) produced by Clostridium botulinum inhibits Ca2+-
dependent acetylcholine (ACh) release (neuroexocytosis) at peripheral neuromuscular …

The bacterium Clostridium botulinum type C produces a progenitor toxin (C16S toxin) that
binds to O-linked sugar chains terminating with sialic acid on the surface of HT-29 cells prior …

C. botulinum C2 toxin and C. perfringens iota toxin belong to the family of actin-ADP-
ribosylating toxins that transfer ADP-ribose from NAD to arginine-l77 of actin. This …

C3-like ADP-ribosyltransferases represent an expanding family of related exoenzymes,
which are produced by Clostridia and various Staphylococcus aureus strains. Here we …

The C2 toxin from Clostridium botulinum represents the prototype of the family of binary actin-
ADP-ribosylating toxins. These toxins covalently transfer ADP-ribose from nicotinamide …

Clostridium botulinum (group-III) is an anaerobic bacterium producing C2 toxin along with
botulinum neurotoxins. C2 toxin is belonged to binary toxin A family in bacterial ADP …

J. Neurochem.(2012) 120, 1084–1096. Abstract C3 ADP‐ribosyltransferase is a valuable
tool to study Rho‐dependent cellular processes. In the current study we investigated the …

Exoenzyme C3 from Clostridium botulinum types C and D specifically ADP-ribosylated a 21-
kilodalton cellular protein, p21. bot. Guanyl nucleotides protected the substrate against …