Lymphatic system in cardiovascular medicine

A Aspelund, MR Robciuc, S Karaman… - Circulation …, 2016 - Am Heart Assoc
The mammalian circulatory system comprises both the cardiovascular system and the
lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a …

Cardiac lymphatics in health and disease

E Brakenhielm, K Alitalo - Nature Reviews Cardiology, 2019 - nature.com
The lymphatic vasculature, which accompanies the blood vasculature in most organs, is
indispensable in the maintenance of tissue fluid homeostasis, immune cell trafficking, and …

Heterogeneity in the lymphatic vascular system and its origin

MH Ulvmar, T Mäkinen - Cardiovascular research, 2016 - academic.oup.com
Lymphatic vessels have historically been viewed as passive conduits for fluid and immune
cells, but this perspective is increasingly being revised as new functions of lymphatic vessels …

Current views on the function of the lymphatic vasculature in health and disease

Y Wang, G Oliver - Genes & development, 2010 - genesdev.cshlp.org
The lymphatic vascular system is essential for lipid absorption, fluid homeostasis, and
immune surveillance. Until recently, lymphatic vessel dysfunction had been associated with …

[HTML][HTML] The lymphatic vasculature revisited

D Kerjaschki - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
Lymphatic vessels constitute a ubiquitous countercurrent system to the blood vasculature
that returns interstitial fluid, salts, small molecules, resorbed fat, and cells to the bloodstream …

The lymphatic vasculature in disease

K Alitalo - Nature medicine, 2011 - nature.com
Blood vessels form a closed circulatory system, whereas lymphatic vessels form a one-way
conduit for tissue fluid and leukocytes. In most vertebrates, the main function of lymphatic …

Promoting lymphangiogenesis and lymphatic growth and remodeling to treat cardiovascular and metabolic diseases

X Liu, K Cui, H Wu, KS Li, Q Peng, D Wang… - … , and vascular biology, 2023 - Am Heart Assoc
Lymphatic vessels are low-pressure, blind-ended tubular structures that play a crucial role in
the maintenance of tissue fluid homeostasis, immune cell trafficking, and dietary lipid uptake …

[HTML][HTML] Lymphatic vessels at the heart of the matter

V Angeli, NL Harvey - Cell Metabolism, 2015 - cell.com
Emergent research in the past decades has brought to light the importance of lymphatic
vessels in tissue homeostasis, immunity, metabolism, and inflammation. In Nature, Klotz et …

[HTML][HTML] Regulation of lymphatic function in obesity

RP Kataru, HJ Park, JE Baik, C Li, J Shin… - Frontiers in …, 2020 - frontiersin.org
The lymphatic system has many functions, including macromolecules transport, fat
absorption, regulation and modulation of adaptive immune responses, clearance of …

Lymphatic vessels in health and disease

CT Kesler, S Liao, LL Munn… - … : Systems Biology and …, 2013 - Wiley Online Library
The lymphatic vasculature plays vital roles in tissue fluid balance, immune defense,
metabolism, and cancer metastasis. In adults, lymphatic vessel formation and remodeling …