Psychiatric disorders entail maladaptive processes impairing individuals' ability to
appropriately interface with environment. Among them, depression is characterized by …

A deeper understanding of the pathomechanisms leading to stress-related psychiatric
disorders is important for the development of more efficient preventive and therapeutic …

Chronic stressors, during developmental sensitive periods and beyond, contribute to the risk
of developing psychiatric conditions, including major depressive disorder (MDD). Epigenetic …

Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple
and partially overlapping sets of susceptibility genes interact each other and with the …

Consolidation of contextual memories after a stressful encounter is essential for the survival
of an organism and in allowing a more appropriate response to be elicited should the …

Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

Depression is a devastating psychiatric disorder caused by a combination of genetic
predisposition and life events, mainly exposure to stress. Early life stress (ELS) in particular …

Susceptibility and resilience to mental disorders result from a complex choreography of
gene–environment interactions with epigenetics at the intersection of external psychological …

Psychiatric disorders are complex multifactorial disorders involving chronic alterations in
neural circuit structure and function. While genetic factors play a role in the etiology of …

Environmental stressors, such as childhood maltreatment, have been recognized to
contribute to the development of depression. Growing evidence suggests that epigenetic …