Vorticity dynamics of a bileaflet mechanical heart valve in an axisymmetric aorta

LP Dasi, L Ge, HA Simon, F Sotiropoulos… - Physics of …, 2007 - pubs.aip.org
We present comprehensive particle image velocimetry measurements and direct numerical
simulation (DNS) of physiological, pulsatile flow through a clinical quality bileaflet …

Three-dimensional study of the effect of two leaflet opening angles on the time-dependent flow through a bileaflet mechanical heart valve

MJ King, T David, J Fisher - Medical engineering & physics, 1997 - Elsevier
A three-dimensional (3-D), time-dependent computational fluid dynamics (CFD) model was
used to investigate the effect of leaflet opening angle on the flow through a fully open …

Direct numerical simulation of the pulsatile flow through an aortic bileaflet mechanical heart valve

MD De Tullio, A Cristallo, E Balaras… - Journal of Fluid …, 2009 - cambridge.org
This work focuses on the direct numerical simulation of the pulsatile flow through a bileaflet
mechanical heart valve under physiological conditions and in a realistic aortic root …

A three-dimensional, time-dependent analysis of flow through a bileaflet mechanical heart valve: comparison of experimental and numerical results

MJ King, J Corden, T David, J Fisher - Journal of biomechanics, 1996 - Elsevier
The flow through a bileaflet mechanical heart valve during the first half of systole was
predicted using computational fluid dynamics (CFD). A three-dimensional model of the …

Flow in a mechanical bileaflet heart valve at laminar and near-peak systole flow rates: CFD simulations and experiments

L Ge, HL Leo, F Sotiropoulos, AP Yoganathan - 2005 - asmedigitalcollection.asme.org
Time-accurate, fully 3D numerical simulations and particle image velocity laboratory
experiments are carried out for flow through a fully open bileaflet mechanical heart valve …

Fluid mechanics of heart valves and their replacements

F Sotiropoulos, TB Le, A Gilmanov - Annual Review of Fluid …, 2016 - annualreviews.org
As the pulsatile cardiac blood flow drives the heart valve leaflets to open and close, the flow
in the vicinity of the valve resembles a pulsed jet through a nonaxisymmetric orifice with a …

High-resolution fluid–structure interaction simulations of flow through a bi-leaflet mechanical heart valve in an anatomic aorta

I Borazjani, L Ge, F Sotiropoulos - Annals of biomedical engineering, 2010 - Springer
We have performed high-resolution fluid–structure interaction simulations of physiologic
pulsatile flow through a bi-leaflet mechanical heart valve (BMHV) in an anatomically realistic …

Simulation of the three-dimensional hinge flow fields of a bileaflet mechanical heart valve under aortic conditions

HA Simon, L Ge, F Sotiropoulos… - Annals of biomedical …, 2010 - Springer
Thromboembolic complications of bileaflet mechanical heart valves (BMHV) are believed to
be due to detrimental stresses imposed on blood elements by the hinge flows …

In Vitro Characterization of Bicuspid Aortic Valve Hemodynamics Using Particle Image Velocimetry

N Saikrishnan, CH Yap, NC Milligan… - Annals of biomedical …, 2012 - Springer
The congenital bicuspid aortic valve (BAV) is associated with increased leaflet calcification,
ascending aortic dilatation, aortic stenosis (AS) and regurgitation (AR). Although underlying …

Computational analysis of an aortic valve jet with Lagrangian coherent structures

SC Shadden, M Astorino, JF Gerbeau - Chaos: An Interdisciplinary …, 2010 - pubs.aip.org
Important progress has been achieved in recent years in simulating the fluid-structure
interaction around cardiac valves. An important step in making these computational tools …