Mitogen-activated protein kinases (MAP kinases) are functionally connected kinases that
regulate key cellular process involved in kidney disease such as all survival, death …

An improved understanding of pathogenic pathways in AKI may identify novel therapeutic
approaches. Previously, we conducted unbiased liquid chromatography-tandem mass …

Mitogen activated protein kinases (MAPKs) are intracellular signal transduction molecules,
which connect cell‐surface receptor signals to intracellular processes. MAPKs regulate a …

Apoptosis signal‐regulating kinase 1 (ASK1) is a member of the mitogen‐activated protein
kinase (MAP3K) family which acts as an upstream regulator for the activation of p38 MAPK …

Renal failure, both acute and chronic, represents an important health problem by its social,
sanitary and economic aspects. Mitogen-activated protein kinases (MAPK) are a family of …

Background. Among mitogen‐activated protein kinase (MAPK) family members, ERK
promotes proliferation or differentiation, whereas JNK and p38 are thought to inhibit cell …

Elevated mitogen-activated protein kinase p38 (p38 MAPK) signaling has been implicated in
various experimental and human glomerulopathies, and its inhibition has proven beneficial …

Tissue hypoxia/ischemia is a pathological feature of many human disorders including stroke,
myocardial infarction, hypoxic/ischemic nephropathy, as well as cancer. In the kidney, the …

Mitogen-activated protein kinases (MAPK) play a key role in the regulation of cellular
processes such as cell growth, cell differentiation, and apoptosis. However, the specific …

CKD affects a large population of patients worldwide. It is characterized by gradual renal
function loss resulting from persistent renal cell death, chronic inflammation, and fibrosis …