Recent studies have revealed that mitogen-activated protein kinase (MAPK) consists of at
least three subfamilies, namely classical MAPK (also known as ERK), stress-activated …

Following an overview of the biochemistry of mitogen-activated protein kinase (MAPK)
pathways, the relevance of these signaling events to specific models of renal cell function …

Acute or chronic kidney injury results from various insults and pathological conditions, and is
accompanied by activation of compensatory repair mechanisms. Both insults and repair …

Stress-induced activation of p38 MAPK and JNK signaling is a feature of both acute and
chronic kidney disease and is associated with disease progression. Inhibitors of p38 MAPK …

Mammalian cells respond to external stimuli by activation of a variety of signal transduction
pathways which culminate in stereotypical responses important in renal disease, such as …

Purpose: Mitogen-activated protein kinases (MAPKs) comprise 3 subgroups, that is
extracellular signal-regulated protein kinase, c-Jun N-terminal kinase (JNK) and p38 MAPK …

We have reported that preconditioning renal tubular cells (RTCs) with A-769662 [a
pharmacological activator of AMP-activated protein kinase (AMPK)] reduces apoptosis of …

Expression of mitogen-activated protein kinase family in rat renal development. Background
Among mitogen-activated protein kinase (MAPK) family members, extracellular signal …

Activation of c-Jun amino kinase (JNK), p38 mitogen-activated protein kinase (MAPK), and
the transcription factor nuclear factor-κB (NF-κB) drives renal inflammation and fibrosis …

Two major stress-activated protein kinases are the p38 mitogen-activated protein kinase
(MAPK) and the c-Jun amino terminal kinase (JNK). p38 and JNK are widely expressed in …