Association of prostate cancer risk loci with disease aggressiveness and prostate cancer–specific mortality
MM Pomerantz, L Werner, W Xie, MM Regan… - Cancer prevention …, 2011 - AACR
Genome-wide association studies have detected more than 30 inherited prostate cancer risk
variants. While clearly associated with risk, their relationship with clinical outcome …
variants. While clearly associated with risk, their relationship with clinical outcome …
Established prostate cancer susceptibility variants are not associated with disease outcome
FE Wiklund, HO Adami, SL Zheng, P Stattin… - … Biomarkers & Prevention, 2009 - AACR
Recent genome-wide association studies have been successful in identifying common
sequence variants associated with prostate cancer risk; however, their importance in …
sequence variants associated with prostate cancer risk; however, their importance in …
Association of prostate cancer risk variants with clinicopathologic characteristics of the disease
J Xu, SD Isaacs, J Sun, G Li, KE Wiley, Y Zhu… - Clinical Cancer …, 2008 - AACR
Purpose: Fifteen independent genetic variants have been implicated in prostate cancer risk
by recent genome-wide association studies. However, their association with …
by recent genome-wide association studies. However, their association with …
Replication of prostate cancer risk loci in a Japanese case–control association study
H Yamada, KL Penney, H Takahashi… - Journal of the …, 2009 - academic.oup.com
Background Two prostate cancer genome-wide scans in populations of European ancestry
identified several genetic variants that are strongly associated with prostate cancer risk. The …
identified several genetic variants that are strongly associated with prostate cancer risk. The …
Risk analysis of prostate cancer in PRACTICAL, a multinational consortium, using 25 known prostate cancer susceptibility loci
A Amin Al Olama, S Benlloch, AC Antoniou… - … , biomarkers & prevention, 2015 - AACR
Background: Genome-wide association studies have identified multiple genetic variants
associated with prostate cancer risk which explain a substantial proportion of familial relative …
associated with prostate cancer risk which explain a substantial proportion of familial relative …
Prostate cancer risk variants are not associated with disease progression
R Szulkin, E Holmberg, P Stattin, J Xu, S Zheng… - The …, 2012 - Wiley Online Library
BACKGROUND Currently used prognostic markers are limited in their ability to accurately
predict disease progression among patients with localized prostate cancer. We examined 23 …
predict disease progression among patients with localized prostate cancer. We examined 23 …
Prostate cancer susceptibility variants confer increased risk of disease progression
I Cheng, SJ Plummer, C Neslund-Dudas… - … , biomarkers & prevention, 2010 - AACR
Background: Genome-wide association studies have identified numerous single nucleotide
polymorphisms (SNP) associated with the risk of prostate cancer. Our objective was to …
polymorphisms (SNP) associated with the risk of prostate cancer. Our objective was to …
Analysis of recently identified prostate cancer susceptibility loci in a population-based study: associations with family history and clinical features
LM FitzGerald, EM Kwon, JS Koopmeiners… - Clinical Cancer …, 2009 - AACR
Purpose: Two recent genome-wide association studies have highlighted several single
nucleotide polymorphisms (SNPs) purported to be associated with prostate cancer risk. We …
nucleotide polymorphisms (SNPs) purported to be associated with prostate cancer risk. We …
Genome-wide association study identifies a genetic variant associated with risk for more aggressive prostate cancer
LM FitzGerald, EM Kwon, MP Conomos, S Kolb… - … , biomarkers & prevention, 2011 - AACR
Abstract Background: Of the 200,000 US men annually diagnosed with prostate cancer,
approximately 20% to 30% will have clinically aggressive disease. Although factors such as …
approximately 20% to 30% will have clinically aggressive disease. Although factors such as …
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer
AA Al Olama, Z Kote-Jarai, SI Berndt, DV Conti… - Nature …, 2014 - nature.com
Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify …
prostate cancer risk predominantly in populations of European ancestry. To identify …