Purpose Congenital primary hypothyroidism (CH) is a state of inadequate thyroid hormone
production detected at birth, caused either by absent, underdeveloped or ectopic thyroid …

Congenital hypothyroidism (CH) is a state of insufficient thyroid hormone supply to the
organism, starting in utero. Two forms of permanent primary or thyroidal CH are known …

Introduction Congenital hypothyroidism (CH) is the most frequent neonatal endocrine
disorder and one of the most common preventable forms of mental retardation worldwide …

Congenital hypothyroidism affects about 1: 3000 to 1: 4000 infants and may be caused by
defects in thyroidal ontogeny or hormone synthesis. The impressive advances in molecular …

Several evidences support a relevant genetic origin for Congenital Hypothyroidism (CH),
however familial forms are uncommon. CH can be due to morphogenetic or functional …

Congenital hypothyroidism due to thyroid dyshormonogenesis is a heterogenic disorder that
may be caused by mutations in any of the known steps in the thyroid hormone biosynthesis …

Congenital hypothyroidism is the most common neonatal metabolic disorder and results in
severe neurodevelopmental impairment and infertility if untreated. Congenital …

Context Congenital hypothyroidism (CH) is the most common neonatal endocrine disorder,
affecting one in 3000 to 4000 newborns. Since the introduction of a newborn screening …

Congenital thyroid gland defects—resulting in reduced production of the hormones
triiodothyronine (T3) and thyroxine (T4)—can be a consequence of either reduced or absent …

Congenital hypothyroidism (CH) may cause severe and irreversible neurologic and
developmental abnormalities when not recognized early. Many millions of newborns have …