The dietary flavones apigenin and luteolin impair smooth muscle cell migration and VEGF expression through inhibition of PDGFR-β phosphorylation
S Lamy, V Bédard, D Labbé, H Sartelet… - Cancer prevention …, 2008 - AACR
Platelet-derived growth factor (PDGF)–dependent recruitment of mural cells such as
pericytes and smooth muscle cells plays a central role in the maturation and stabilization of …
pericytes and smooth muscle cells plays a central role in the maturation and stabilization of …
Delphinidin, a dietary anthocyanidin, inhibits platelet-derived growth factor ligand/receptor (PDGF/PDGFR) signaling
S Lamy, E Beaulieu, D Labbé, V Bédard… - …, 2008 - academic.oup.com
Most cancers are dependent on the growth of tumor blood vessels and inhibition of tumor
angiogenesis may thus provide an efficient strategy to retard or block tumor growth …
angiogenesis may thus provide an efficient strategy to retard or block tumor growth …
Chrysin restores PDGF-induced inhibition on protein tyrosine phosphatase and reduces PDGF signaling in cultured VSMCs
HM Lo, MW Wu, SL Pan, CY Peng, PH Wu… - The Journal of Nutritional …, 2012 - Elsevier
Previous studies have shown that an increased intake of dietary flavonoids is associated
with a decreased risk of cardiovascular diseases (CVDs). PDGF is a major mitogen for …
with a decreased risk of cardiovascular diseases (CVDs). PDGF is a major mitogen for …
Combined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound
L Labrecque, S Lamy, A Chapus, S Mihoubi… - …, 2005 - academic.oup.com
The vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF)
receptors play essential and complementary roles in angiogenesis and combined inhibition …
receptors play essential and complementary roles in angiogenesis and combined inhibition …
Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation
S Lamy, M Blanchette, J Michaud-Levesque… - …, 2006 - academic.oup.com
Epidemiological studies have shown that a diet rich in fruits and vegetables has a beneficial
preventive effect on cardiovascular diseases and cancer by mechanisms that have not yet …
preventive effect on cardiovascular diseases and cancer by mechanisms that have not yet …
Apigenin attenuates neointima formation via suppression of vascular smooth muscle cell phenotypic transformation
H Guan, L Gao, L Zhu, L Yan, M Fu… - Journal of Cellular …, 2012 - Wiley Online Library
Abnormal proliferation, migration, and phenotypic modulation of vascular smooth muscle
cells (VSMCs) are critical factors in neointima formation during restenosis. The purpose of …
cells (VSMCs) are critical factors in neointima formation during restenosis. The purpose of …
Lycopene binds PDGF-BB and inhibits PDGF-BB-induced intracellular signaling transduction pathway in rat smooth muscle cells
Cardiovascular diseases (CVDs) result from the sub-endothelial accumulation of
inflammatory cells and smooth muscle cells (SMCs). Lycopene, a natural compound from …
inflammatory cells and smooth muscle cells (SMCs). Lycopene, a natural compound from …
Pelargonidin attenuates PDGF-BB-induced aortic smooth muscle cell proliferation and migration by direct inhibition of focal adhesion kinase
Pelargonidin is a natural red pigment found in fruits and vegetables, and has been reported
to exhibit various effects potentially beneficial for human health. However, the possible …
to exhibit various effects potentially beneficial for human health. However, the possible …
A naturally occurring carotenoid, lutein, reduces PDGF and H2O2 signaling and compromises migration in cultured vascular smooth muscle cells
HM Lo, YJ Tsai, WY Du, CJ Tsou, WB Wu - Journal of biomedical Science, 2012 - Springer
Background Platelet-derived growth factor (PDGF) is a potent stimulator of growth and
motility of vascular smooth muscle cells (VSMCs). Abnormalities of PDGF/PDGF receptor …
motility of vascular smooth muscle cells (VSMCs). Abnormalities of PDGF/PDGF receptor …
Epigallocatechin-3-gallate inhibits the PDGF-induced VEGF expression in human vascular smooth muscle cells via blocking PDGF receptor and Erk-1/2
JS Park, MH Kim, HJ Chang… - International …, 2006 - spandidos-publications.com
Platelet-derived growth factor (PDGF) has been known to induce vascular endothelial
growth factor (VEGF) expression in human vascular smooth muscle cells (hVSMCs). We …
growth factor (VEGF) expression in human vascular smooth muscle cells (hVSMCs). We …