Platelet-derived growth factor (PDGF) is a potent stimulator of growth and motility of smooth
muscle cells (SMCs) and fibroblasts. Abnormalities of PDGF/PDGF receptor (PDGFR) are …

Epidemiological studies have shown that a diet rich in fruits and vegetables might reduce
the risk of cardiovascular diseases and protect against cancer by mechanisms that have not …

Abstract Proanthocyanidin A2 (PA2), one of A-type proanthocyanidins, has been shown to
harbor a broad spectrum of pharmacological activities, including anti-inflammatory …

Epigallocatechin gallate (EGCG) is known to exhibit antioxidant, antiproliferative, and
antithrombogenic effects and reduce the risk of cardiovascular diseases. Key events in the …

Background and purpose: Red wine polyphenols (RWPs) inhibit the expression of vascular
endothelial growth factor (VEGF), a major pro‐angiogenic and pro‐atherosclerotic factor, in …

The vasculoprotective properties of delphinidin are driven mainly by its action on endothelial
cells. Moreover, delphinidin displays anti-angiogenic properties in both in vitro and in vivo …

The abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) leads to
intimal thickening of the aorta and is, therefore, important in the development of …

Diet can be one of the most important factors that influence risks for cardiovascular diseases.
Hesperetin, a flavonoid present in grapefruits and oranges, is one candidate that may …

Tangeretin, a natural polymethoxylated flavone concentrated in the peel of citrus fruits, is
known to have antiproliferative, antiinvasive, antimetastatic and antioxidant activities …

In an attempt to identify phytochemicals contributing to the well-documented preventive
effect of plant-based diets on cancer incidence and mortality, we have previously shown that …