[HTML][HTML] The many faces of matrix metalloproteinase-7 in kidney diseases

Z Liu, RJ Tan, Y Liu - Biomolecules, 2020 - mdpi.com
Matrix metalloproteinase-7 (MMP-7) is a secreted zinc-dependent endopeptidase that is
implicated in regulating kidney homeostasis and diseases. MMP-7 is produced as an …

[HTML][HTML] Matrix metalloproteinase-10 in kidney injury repair and disease

X Sun, Y Liu - International Journal of Molecular Sciences, 2022 - mdpi.com
Matrix metalloproteinase-10 (MMP-10) is a zinc-dependent endopeptidase with the ability to
degrade a broad spectrum of extracellular matrices and other protein substrates. The …

[HTML][HTML] Matrix metalloproteinases-7 and kidney fibrosis

B Ke, C Fan, L Yang, X Fang - Frontiers in physiology, 2017 - frontiersin.org
Matrix metalloproteinase-7 (MMP-7) is a secreted zinc-and calcium-dependent
endopeptidase that degrades a broad range of extracellular matrix substrates and additional …

[HTML][HTML] Matrix metalloproteinase-7 protects against acute kidney injury by priming renal tubules for survival and regeneration

H Fu, D Zhou, H Zhu, J Liao, L Lin, X Hong, FF Hou… - Kidney international, 2019 - Elsevier
Matrix metalloproteinase-7 (MMP-7) is a secreted endopeptidase that degrades a broad
range of substrates. Recent studies have identified MMP-7 as an early biomarker to predict …

Matrix metalloproteinase-7 is a urinary biomarker and pathogenic mediator of kidney fibrosis

D Zhou, Y Tian, L Sun, L Zhou, L Xiao… - Journal of the …, 2017 - journals.lww.com
Abstract Matrix metalloproteinase-7 (MMP-7), a secreted zinc–and calcium–dependent
endopeptidase, is a transcriptional target of canonical Wnt/β-catenin signaling. Because …

[HTML][HTML] Matrix metalloproteinases contribute to kidney fibrosis in chronic kidney diseases

H Zhao, Y Dong, X Tian, TK Tan, Z Liu… - World journal of …, 2013 - ncbi.nlm.nih.gov
Matrix metalloproteinases (MMPs) are members of the neutral proteinase family. They were
previously thought to be anti-fibrotic because of their ability to degrade and remodel of …

[HTML][HTML] Leukocyte-derived MMP9 is crucial for the recruitment of proinflammatory macrophages in experimental glomerulonephritis

MA Kluger, G Zahner, HJ Paust, M Schaper… - Kidney international, 2013 - Elsevier
Matrix metalloproteinase 9 (MMP9) is a conditionally expressed enzyme and is upregulated
in glomerulonephritis. Its function in these diseases, however, remains to be fully elucidated …

[HTML][HTML] Matrix metalloproteinase-7 promotes chronic kidney disease progression via the induction of inflammasomes and the suppression of autophagy

CM Zheng, KC Lu, YJ Chen, CY Li, YH Lee… - Biomedicine & …, 2022 - Elsevier
Deposition of extracellular matrix (ECM), epithelial-mesenchymal transition (EMT) and
inflammation are crucial processes in chronic kidney disease (CKD) progression. The matrix …

[HTML][HTML] MMP-2 and 9 in chronic kidney disease

Z Cheng, MH Limbu, Z Wang, J Liu, L Liu… - International journal of …, 2017 - mdpi.com
Gelatinases are members of the matrix metalloproteinase (MMPs) family; they play an
important role in the degradation of the extracellular matrix (ECM). This effect is also crucial …

Matrix metalloproteinases in kidney homeostasis and diseases

RJ Tan, Y Liu - American journal of physiology-renal …, 2012 - journals.physiology.org
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that have
been increasingly linked to both normal physiology and abnormal pathology in the kidney …