Estrogens are the primary female sex hormones and play important roles in both
reproductive and non-reproductive systems. Estrogens can be synthesized in non …

Over the last decades estrogen has been recognized to be involved in normal brain function
due to its neurothrophic and neuroprotective effects. Estrogen is intimately associated with …

Estrogen facilitates higher cognitive functions by exerting effects on brain regions such as
the prefrontal cortex and hippocampus. Estrogen induces spinogenesis and synaptogenesis …

We now appreciate that estrogen is a pleiotropic gonadal steroid that exerts profound effects
on the plasticity and cell survival of the adult brain. Over the past century, the life span of …

The female sex hormone estrogen has been ascribed potent neuroprotective properties. It
signals by binding and activating estrogen receptors that, depending on receptor subtype …

Estrogens play a crucial physiological function in the brain; however, debates exist
concerning the role of estrogens in Alzheimer's disease (AD). Women during pre-, peri-, or …

[Frontiers in Bioscience 10, 257--267, January 1, 2005] 257 ESTROGEN AND BRAIN:
SYNTHESIS, FUNCTION AND DISEASES Rena Li 1 and Page 1 [Frontiers in Bioscience 10 …

In recent years, the knowledge of how estrogen interferes with mammalian brain functions
and development has broadened substantially. In the adult brain, estrogen is not only …

While estrogens are well known for their pivotal role in the female reproductive system, they
also play a crucial function in regulating physiological processes associated with learning …

Estrogens have direct effects on the brain areas controlling cognition. One of the most
studied of these regions is the dorsal hippocampal formation, which governs the formation of …