The majority of cancers are associated to cachexia, a severe form of weight loss mostly
accounted for by skeletal muscle wasting. Cancer patients are often treated with …

A compounding feature of greater than 50% of all cancers is the high incidence of the
cachexia syndrome, a complex metabolic disorder characterized by extreme weight loss due …

Simple Summary In addition to cancer-related factors, anti-cancer chemotherapy treatment
can drive life-threatening body wasting in a syndrome known as cachexia. Emerging …

Skeletal muscle weakness is a debilitating consequence of many malignancies. Muscle
weakness has a negative impact on both patient wellbeing and outcome in a range of …

Cachexia represents one of the primary complications of colorectal cancer due to its effects
on depletion of muscle and fat. Evidence suggests that chemotherapeutic regimens, such as …

Breast cancer represents the most commonly diagnosed cancer while neoadjuvant and
adjuvant chemotherapies are extensively used in order to reduce tumor development and …

Cancer cachexia—cancer-associated body weight and muscle loss—is a significant
predictor of mortality and morbidity in cancer patients across a variety of cancer types …

Platinum-based drugs are among the most effective anticancer therapies, integrating the
standard of care for numerous human malignancies. However, platinum-based …

Cancer cachexia is a severe and disabling clinical condition that frequently accompanies
the development of many types of cancer. Muscle wasting is the hallmark of cancer cachexia …

Progressive skeletal muscle wasting in cancer cachexia involves a process of dysregulated
protein synthesis and breakdown. This catabolism may be the result of mal‐nutrition, and an …