[HTML][HTML] Biomaterial-mediated intracellular control of macrophages for cell therapy in pro-inflammatory and pro-fibrotic conditions
Macrophages are key modulators of all inflammatory diseases and essential for their
resolution, making macrophage cell therapy a promising strategy for regenerative medicine …
resolution, making macrophage cell therapy a promising strategy for regenerative medicine …
Modulation of macrophage phenotype via phagocytosis of drug‐loaded microparticles
Monocyte‐derived macrophages play a critical role in directing wound pathology following
injury. Depending on their phenotype, macrophages also promote tissue regeneration …
injury. Depending on their phenotype, macrophages also promote tissue regeneration …
Biomaterial-mediated reprogramming of monocytes via microparticle phagocytosis for sustained modulation of macrophage phenotype
Monocyte-derived macrophages orchestrate tissue regeneration by homing to sites of injury,
phagocytosing pathological debris, and stimulating other cell types to repair the tissue …
phagocytosing pathological debris, and stimulating other cell types to repair the tissue …
Biomaterial-assisted macrophage cell therapy for regenerative medicine
S Sung, LA Steele, GE Risser, KL Spiller - Advanced drug delivery reviews, 2023 - Elsevier
Although most tissue types are capable of some form of self-repair and regeneration, injuries
that are larger than a critical threshold or those occurring in the setting of certain diseases …
that are larger than a critical threshold or those occurring in the setting of certain diseases …
Harnessing macrophage plasticity for tissue regeneration
Macrophages are versatile and plastic effector cells of the immune system, and contribute to
diverse immune functions including pathogen or apoptotic cell removal, inflammatory …
diverse immune functions including pathogen or apoptotic cell removal, inflammatory …
Drug delivery strategies to control macrophages for tissue repair and regeneration
R Garash, A Bajpai… - Experimental biology …, 2016 - journals.sagepub.com
Tissue repair and regeneration is a complex process. Our bodies have an excellent capacity
to regenerate damaged tissues in many situations. However, tissue healing is impaired in …
to regenerate damaged tissues in many situations. However, tissue healing is impaired in …
Biomaterials and bioactive factor delivery systems for the control of macrophage activation in regenerative medicine
Macrophages play an important role in tissue repair, regeneration, and the ability of
biomaterials to mediate these processes. Macrophages are highly plastic cells that exhibit …
biomaterials to mediate these processes. Macrophages are highly plastic cells that exhibit …
Potential effects of biomaterials on macrophage function and their signalling pathways
F Zhu, S Wang, X Zhu, C Pang, P Cui, F Yang… - Biomaterials …, 2023 - pubs.rsc.org
The use of biomaterials in biomedicine and healthcare has increased in recent years.
Macrophages are the primary immune cells that induce inflammation and tissue repair after …
Macrophages are the primary immune cells that induce inflammation and tissue repair after …
Biomaterials-mediated regulation of macrophage cell fate
Endogenous regeneration aims to rebuild and reinstate tissue function through enlisting
natural self-repairing processes. Promoting endogenous regeneration by reducing tissue …
natural self-repairing processes. Promoting endogenous regeneration by reducing tissue …
Sustained release of drug-loaded nanoparticles from injectable hydrogels enables long-term control of macrophage phenotype
Injectable hydrogels may be pre-formed through dynamic crosslinks, allowing for injection
and subsequent retention in the tissue by shear-thinning and self-healing processes …
and subsequent retention in the tissue by shear-thinning and self-healing processes …