Acral and mucosal melanomas arise from sun-protected sites, disproportionately impact
darker-skinned individuals, and exact higher mortality than common types of cutaneous …

8568 Background: Mutations in KIT, BRAF, NRAS and PDGFRA are common in melanoma,
which have not been extensively studied in Asia. We examined these aberrations and …

Purpose: Recent studies have shown activating KIT mutations in melanoma originating from
mucosa, acral, or cumulative sun-damaged skin sites. We aimed to assess the predictive …

This study aimed to evaluate the association of KIT mutations with clinicopathologic features
of melanomas using a meta-analysis and to identify differences between Asian and White …

Activating mutations in either BRAF or NRAS are seen in a significant number of malignant
melanomas, but their incidence appears to be dependent to ultraviolet light exposure. Thus …

Despite multiple clinical trials utilizing a spectrum of therapeutic modalities, melanoma
remains a disease with dismal outcomes in patients with advanced disease. However, it is …

Background Mucosal melanoma is the second most common subtype of melanoma in China
and head and neck region is one of the main sites of this disease. Aims/Objectives Analyzed …

Similar to other malignancies, TCGA network efforts identified the detailed genomic picture
of skin melanoma, laying down the basis of molecular classification. On the other hand …

Mucosal melanoma is a rare and aggressive subtype of melanoma that has a less favorable
prognosis due to the lack of understanding and identification of oncogenic drivers. Recently …

Acral and mucosal melanoma are uncommon variants of melanoma. Acral melanoma has
an age-adjusted incidence of approximately 1.8 cases per million individuals per year …