Aggressive red blood cell transfusion: no association with improved outcomes for victims of isolated traumatic brain injury

ME George, DE Skarda, CR Watts, HD Pham… - Neurocritical care, 2008 - Springer
Background Clinical studies have caused blood transfusion practices in critically ill patients
to become more conservative in the last decade. However, few studies have focused on …

Safety and cost efficiency of a restrictive transfusion protocol in patients with traumatic brain injury

LB Ngwenya, CG Suen, PE Tarapore, GT Manley… - Journal of …, 2017 - thejns.org
OBJECTIVE Blood loss and moderate anemia are common in patients with traumatic brain
injury (TBI). However, despite evidence of the ill effects and expense of the transfusion of …

Red blood cell transfusion in patients with traumatic brain injury: a systematic review and meta-analysis

A Boutin, M Chassé, M Shemilt, F Lauzier… - Transfusion medicine …, 2016 - Elsevier
Our objectives were to evaluate the frequency of red blood cell (RBC) transfusion in patients
with traumatic brain injury (TBI) as well as potential determinants and outcomes associated …

Hemoglobin thresholds and red blood cell transfusion in adult patients with moderate or severe traumatic brain injuries: a retrospective cohort study

A Boutin, L Moore, RS Green, R Zarychanski… - Journal of critical …, 2018 - Elsevier
Purpose We aimed to evaluate the association between transfusion practices and clinical
outcomes in patients with traumatic brain injury. Material and methods We conducted a …

Transfusion of red blood cells in patients with traumatic brain injuries admitted to Canadian trauma health centres: a multicentre cohort study

A Boutin, L Moore, F Lauzier, M Chassé, S English… - BMJ open, 2017 - bmjopen.bmj.com
Background Optimisation of healthcare practices in patients sustaining a traumatic brain
injury is of major concern given the high incidence of death and long-term disabilities …

Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury

LA McIntyre, DA Fergusson, JS Hutchison… - Neurocritical care, 2006 - Springer
Objective To compare a restrictive versus a liberal transfusion strategy in patients with
moderate to severe closed head injury following multiple trauma in 13 Canadian intensive …

[HTML][HTML] TRansfusion strategies in Acute brain INjured patients (TRAIN): a prospective multicenter randomized interventional trial protocol

FS Taccone, R Badenes, CB Rynkowski, P Bouzat… - Trials, 2023 - Springer
Background Although blood transfusions can be lifesaving in severe hemorrhage, they can
also have potential complications. As anemia has also been associated with poor outcomes …

Red blood cell transfusion in critically ill patients with traumatic brain injury: an international survey of physicians' attitudes

PL Bonaventure, F Lauzier… - Canadian Journal …, 2019 - research.monash.edu
Abstract© 2019, Canadian Anesthesiologists' Society. Introduction: Restrictive transfusion
strategies have been advocated in critically ill patients. Nevertheless, considerable …

Transfusions and long-term functional outcomes in traumatic brain injury

MA Warner, T O'Keeffe, P Bhavsar, R Shringer… - Journal of …, 2010 - thejns.org
Object In this paper, the authors' goal was to examine the relationship between transfusion
and long-term functional outcomes in moderately anemic patients (lowest hematocrit [HCT] …

Retrospective evaluation of anemia and transfusion in traumatic brain injury

AP Carlson, CR Schermer, SW Lu - Journal of Trauma and Acute …, 2006 - journals.lww.com
Background: Despite clear evidence in critical care that blood transfusion has an adverse
impact on outcome, neurosurgical textbooks still recommend transfusion of patients with …