Tumor treating fields: a comprehensive overview of the underlying molecular mechanism

P Hong, N Kudulaiti, S Wu, J Nie… - Expert review of …, 2022 - Taylor & Francis
Introduction As a novel treatment modality, tumor treating fields (TTFields) exert low-
intensity, medium-frequency electric fields on tumor cells. TTFields' effectiveness and safety …

Therapeutic potential of tumor treating fields for malignant brain tumors

Y Zhou, X Xing, J Zhou, H Jiang, P Cen, C Jin… - Cancer …, 2023 - Wiley Online Library
Background Malignant brain tumors are among the most threatening diseases of the central
nervous system, and despite increasingly updated treatments, the prognosis has not been …

Tumor-treating fields: a fourth modality in cancer treatment

EJ Mun, HM Babiker, U Weinberg, ED Kirson… - Clinical Cancer …, 2018 - AACR
Despite major advances in therapy, cancer continues to be a leading cause of mortality. In
addition, toxicities of traditional therapies pose a significant challenge to tolerability and …

[HTML][HTML] Tumor-treating fields in glioblastomas: past, present, and future

X Guo, X Yang, J Wu, H Yang, Y Li, J Li, Q Liu, C Wu… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma (GBM) is the most common malignant primary brain tumor.
Although the standard of care, including maximal resection, concurrent radiotherapy with …

[HTML][HTML] Tumor treating fields: at the crossroads between physics and biology for cancer treatment

FA Carrieri, C Smack, I Siddiqui, LR Kleinberg… - Frontiers in …, 2020 - frontiersin.org
Despite extraordinary advances that have been achieved in the last few decades, cancer
continues to represent a leading cause of mortality worldwide. Lethal cancer types ultimately …

[PDF][PDF] Anti-cancer mechanisms of action of therapeutic alternating electric fields (tumor treating fields [TTFields])

S Shams, CB Patel - Journal of molecular cell biology, 2022 - academic.oup.com
Despite improved survival outcomes across many cancer types, the prognosis remains grim
for certain solid organ cancers including glioblastoma and pancreatic cancer. Invariably in …

An overview of potential novel mechanisms of action underlying Tumor Treating Fields-induced cancer cell death and their clinical implications

NK Karanam, MD Story - International journal of radiation biology, 2021 - Taylor & Francis
Traditional cancer therapy choices for clinicians are surgery, chemotherapy, radiation and
immune therapy which are used either standalone therapies or in various combinations …

The clinical application of tumor treating fields therapy in glioblastoma

MM Riley, P San, E Lok, KD Swanson… - JoVE (Journal of …, 2019 - jove.com
Glioblastoma is the most common and lethal form of brain cancer, with a median survival of
15 months after diagnosis and a 5 year survival rate of only 5% with current standard of care …

Tumor-Treating Fields: A fourth modality in cancer treatment, new practice updates

R Arvind, SR Chandana, MJ Borad… - Critical Reviews in …, 2021 - Elsevier
Although major innovations in treatment are advancing, cancer persists as one of the
leading causes of mortality. With the rising incidence of cancer and as we treat them …

[HTML][HTML] The schemes, mechanisms and molecular pathway changes of Tumor Treating Fields (TTFields) alone or in combination with radiotherapy and chemotherapy

G Tanzhu, L Chen, G Xiao, W Shi, H Peng… - Cell Death …, 2022 - nature.com
Abstract Tumor Treating Fields (TTFields) is a physical therapy that uses moderate
frequency (100–300 kHz) and low-intensity (1–3 V/cm) alternating electric fields to inhibit …