The first human heart transplantation was performed by Christian Barnard in 1967. While the
technical aspect had been worked out, allograft rejection was a major limitation in the early …

Recent advances in the management of heart transplant recipients have resulted in
improved survival, particularly in the early post-transplant period. Although graft rejection …

Survival after cardiac transplantation has improved progressively since its inception over 35
years ago, with current 1 year survival approaching 90% and 7 year survival approaching …

There has been significant progress in the field of heart transplantation over the last 45
years. The 1-yr survival rates following heart transplantation have improved from 30% in the …

▪ Abstract Heart transplantation has evolved over the past 30 years into a mainstay of
therapy for heart failure patients. As the surgical technique and basic immunology were …

With the introduction of cyclosporin A in the early 1980s, heart transplantation was
transformed from an experimental procedure into a successful therapeutic option for patients …

Heart transplantation has become a standard therapy option for advanced heart failure. The
translation of heart transplantation from innovative experiments to long-term clinical success …

Abstract Purpose of Review The purpose of this review is to provide a comprehensive
update on recent advances in heart transplantation. Recent Findings Heart transplantation is …

In more than 35 years of experience with heart transplantation, improvements in patient
selection, surgical techniques, organ preservation, and postoperative management have …

Despite advances in pharmacologic and device treatment of chronic heart failure, long-term
morbidity and mortality remain high, and many patients progress to end-stage heart failure …