The general issue of weaning can be viewed as composed of three different groups of
patients. First, simple or easy weaning, represents 60% to 70% of patients whose first trial of …

This article reviews the factors that determine a patient's ability to resume spontaneous
breathing following a period of mechanical ventilation, the use of physiologic measurements …

We have previously shown (Am. J. Respir. Crit. Care Med. 1995; 152: 1248–1255) that in
patients needing mechanical ventilation, the load imposed on the inspiratory muscles is …

Intubation and mechanical ventilation are routine and life-saving procedures. The
percentage of patients receiving ventilatory support in the critical care setting varies between …

Weaning patients from mechanical ventilation constitutes a major portion of the workload in
an intensive care unit, as over 40% of total ventilator time is consumed by the weaning …

Weaning from mechanical ventilation is a period of transition from total ventilatory support to
spontaneous breathing. It represents a relevant clinical problem because as many as 25 …

For many critically ill patients admitted to an intensive care unit, the insertion of an
endotracheal tube and the initiation of mechanical ventilation (MV) can be lifesaving …

For most mechanically ventilated patients, weaning can be accomplished quickly and easily.
However, there is a smaller group of ventilated patients who fail to wean and remain …

The study of patients being weaned from mechanical ventilation has offered new insights
into the physiology of respiratory failure. Assessment of the balance between respiratory …

For most patients who require mechanical ventilation weaning and extubation is simple. In
these patients a variety of strategies can be successful. In addition, sim ple criteria may …