Nutritional and metabolic factors in amyotrophic lateral sclerosis

A Ludolph, L Dupuis, E Kasarskis, F Steyn… - Nature Reviews …, 2023 - nature.com
Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that is
classically thought to impact the motor system. Over the past 20 years, research has started …

Altered metabolic homeostasis in amyotrophic lateral sclerosis: mechanisms of energy imbalance and contribution to disease progression

ZA Ioannides, ST Ngo, RD Henderson… - Neurodegenerative …, 2016 - karger.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the death of motor neurones, which leads to paralysis and death in an average of 3 years …

Metabolic dysfunctions in amyotrophic lateral sclerosis pathogenesis and potential metabolic treatments

TW Tefera, K Borges - Frontiers in neuroscience, 2017 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease primarily
characterized by loss of motor neurons in brain and spinal cord. The death of motor neurons …

Nutritional state, energy intakes and energy expenditure of amyotrophic lateral sclerosis (ALS) patients

L Genton, V Viatte, JP Janssens, AC Héritier, C Pichard - Clinical nutrition, 2011 - Elsevier
Amyotrophic lateral sclerosis (ALS) alters nutritional state, energy intake and energy
expenditure. This article aims at reviewing present knowledge on these topics in order to …

Metabolic abnormalities, dietary risk factors and nutritional management in amyotrophic lateral sclerosis

E D'Amico, G Grosso, JW Nieves, A Zanghì… - Nutrients, 2021 - mdpi.com
Amyotrophic Lateral Sclerosis (ALS) is a devastating progressive neurodegenerative
disease that affects motor neurons, leading to a relentless paralysis of skeletal muscles and …

Energy metabolism in ALS: an underappreciated opportunity?

T Vandoorne, K De Bock, L Van Den Bosch - Acta neuropathologica, 2018 - Springer
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal
neurodegenerative disorder that primarily affects motor neurons. Despite our increased …

Nutrition and dietary supplements in motor neuron disease

J Rosenfeld, A Ellis - Physical medicine and rehabilitation clinics of North …, 2008 - Elsevier
Compromised nutrition leading to weight loss is a common and significant problem in the
amyotrophic lateral sclerosis (ALS) patient population. The benefit of aggressive and early …

Do patients with amyotrophic lateral sclerosis (ALS) have increased energy needs?

N Vaisman, M Lusaus, B Nefussy, E Niv… - Journal of the …, 2009 - Elsevier
BACKGROUND AND AIMS: Nutritional status is a prognostic factor for survival in
amyotrophic lateral sclerosis (ALS) patients. We investigated the contribution of some of the …

CNS glucose metabolism in Amyotrophic Lateral Sclerosis: a therapeutic target?

TW Tefera, FJ Steyn, ST Ngo, K Borges - Cell & bioscience, 2021 - Springer
Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disorder
primarily characterized by selective degeneration of both the upper motor neurons in the …

[HTML][HTML] Body mass index and dietary intervention: implications for prognosis of amyotrophic lateral sclerosis

ST Ngo, FJ Steyn, PA McCombe - Journal of the neurological sciences, 2014 - Elsevier
Amyotrophic lateral sclerosis (ALS) is an adult onset, neurodegenerative disease that is
characterized by the loss of upper (corticospinal) and lower motor neurons. ALS is a …