Aim The aim of the study was to assess the consequences of early and systematic nutritional
intervention on the clinical conditions of amyotrophic lateral sclerosis (ALS) patients and on …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by loss of motor neurons in the spinal cord, brain stem and motor cortex which …

Objective To determine the prevalence of hypermetabolism, relative to body composition, in
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …

Adequate nutritional support and high body mass index (BMI) are good prognostic factors for
disease progression and survival in amyotrophic lateral sclerosis (ALS). However, whether …

Objectives: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease,
and the nutritional state of ALS patients is associated with survival. The purpose of the …

Importance Because dietary intake may influence pathophysiologic mechanisms in sporadic
amyotrophic lateral sclerosis (ALS), the association between premorbid dietary intake and …

Highlights•Comparing agents used in ALS animal models by onset, survival and muscle
damage.•Agents are organized by individual mechanisms and effects summarized.•Analysis …

Strong evidence shows that mitochondrial dysfunction is involved in amyotrophic lateral
sclerosis (ALS), but despite the fact that mitochondria play a central role in excitotoxicity …

Our objective was to investigate the nutritional requirements in ALS and to determine the
feasibility of early intervention with NIPPV. Subjects were enrolled into one of two arms. In …

In the present article, we review the many facets of mitochondrial dysfunction in amyotrophic
lateral sclerosis (ALS), a fatal neurodegenerative disease due to loss of upper motor …