Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …

The lung is continuously exposed to inhaled pollutants, microbes and allergens. Therefore,
the pulmonary immune system has to defend against harmful pathogens, while an …

Surfactant protein D (SP-D) is a member of the collectin family of the innate host defense
proteins. In the lung, SP-D is expressed primarily by type II cells. Gene-targeted SP-D …

The lung is repeatedly exposed to inhaled particles and pathogens that are cleared by the
actions of a multi-component innate host defense system. The pulmonary collectins …

The collectin surfactant protein D (SP-D) is an important component of the pulmonary innate
immune system, but SP-D is also present on extrapulmonary epithelial surfaces and in …

Abstract Surfactant protein D (SP-D) plays important roles in the host defense against
infectious microorganisms and in regulating the innate immune response to a variety of …

Surfactant proteins SP-A and SP-D are hydrophilic, collagen-containing calcium-dependent
lectins, which appear to have a range of innate immune functions at pulmonary as well as …

Pulmonary surfactant, a complex of lipids and proteins, functions to keep alveoli from
collapsing at expiration. Surfactant proteins A (SP-A) and D (SP-D) belong to the collectin …

Surfactant proteins A (SP-A) and D (SP-D) have been implicated in pulmonary innate
immunity. The proteins are host defense lectins, belonging to the collectin family which also …

Abstract Surfactant protein-D (SP-D) participates in the innate response to inhaled
microorganisms and organic antigens, and contributes to immune and inflammatory …