[HTML][HTML] An open-label expanded access program of afatinib in EGFR tyrosine kinase inhibitor-naïve patients with locally advanced or metastatic non-small cell lung …

K Park, JS Kim, JH Kim, YC Kim, HG Kim, EK Cho… - BMC cancer, 2021 - Springer
Background Afatinib is approved globally for EGFR-TKI treatment-naïve patients with EGFR
mutation-positive non-small cell lung cancer (NSCLC). In this Korean expanded access …

[HTML][HTML] Afatinib in EGFR TKI-Naïve patients with locally advanced or metastatic EGFR mutation-positive non-small cell lung cancer: a pooled analysis of three phase …

A Passaro, F de Marinis, HY Tu, KK Laktionov… - Frontiers in …, 2021 - frontiersin.org
Background Afatinib is approved for first-line treatment of patients with epidermal growth
factor receptor mutation-positive (EGFR m+) non-small-cell lung cancer (NSCLC). Here, we …

[HTML][HTML] Real-world experience of afatinib as first-line therapy for advanced EGFR mutation-positive non-small cell lung cancer in Korea

SY Lee, CM Choi, YS Chang, KY Lee… - … lung cancer Research, 2021 - ncbi.nlm.nih.gov
Background We investigated the clinical characteristics and treatment outcomes of Korean
patients receiving first-line afatinib for advanced epidermal growth factor receptor mutation …

[HTML][HTML] Afatinib in EGFR TKI-naïve patients with locally advanced or metastatic EGFR mutation-positive non-small cell lung cancer: Interim analysis of a Phase 3b …

F de Marinis, KK Laktionov, A Poltoratskiy, I Egorova… - Lung Cancer, 2021 - Elsevier
Objectives Randomized controlled trials have demonstrated that afatinib is a suitable
treatment option for patients with epidermal growth factor receptor mutation-positive …

[HTML][HTML] Real-world first-line afatinib for advanced EGFR mutation-positive non-small cell lung cancer in Korea: updated survival data

J Choi, CM Choi, YS Chang, KY Lee… - Translational Lung …, 2023 - ncbi.nlm.nih.gov
Background Data from clinical trials and real-world studies show that afatinib is effective in
treating non-small cell lung cancer (NSCLC) harboring activating mutations in the epidermal …

Afatinib as first-line treatment in patients with EGFR-mutated non-small cell lung cancer in routine clinical practice

WM Brückl, M Reck, F Griesinger… - Therapeutic …, 2021 - journals.sagepub.com
Background: Lung cancer is a leading cause of cancer-related death in Germany and
worldwide. Non-small cell lung cancer (NSCLC) comprises~ 80% of lung cancer diagnoses; …

[HTML][HTML] A real-world experience of first-line afatinib in Korean patients with EGFR-mutant non-small cell lung cancer

SH Yoon, YS Kim, JH Chung, HY Seol, MH Kim - Annals of Oncology, 2019 - Elsevier
Background Afatinib is indicated for the treatment of EGFR mutation-positive (M+) non-small
cell lung cancer (NSCLC). LUX-Lung trials have demonstrated that afatinib significantly …

[HTML][HTML] A Phase IIIb Open-Label, Single-Arm Study of Afatinib in EGFR TKI-Naïve Patients with EGFRm+ NSCLC: Final Analysis, with a Focus on Patients Enrolled at …

HY Tu, J Feng, M Shi, J Zhao, Y Wang, J Chang… - Targeted Oncology, 2022 - Springer
Background Afatinib has been shown as a suitable option for the treatment of epidermal
growth factor receptor mutation-positive (EGFR m+) non-small-cell lung cancer (NSCLC) in …

[HTML][HTML] Afatinib as First-Line Treatment in Asian Patients with EGFR Mutation-Positive NSCLC: A Narrative Review of Real-World Evidence

S Lu, JY Shih, TW Jang, CK Liam, Y Yu - Advances in therapy, 2021 - Springer
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) are a standard of
care in the first-line treatment of patients with EGFR mutation-positive metastatic non-small …

First-line afatinib for the treatment of EGFR mutation-positive non-small-cell lung cancer in the 'real-world' clinical setting

K Park, D Wan-Teck Lim, I Okamoto… - … advances in medical …, 2019 - journals.sagepub.com
Afatinib is an ErbB family blocker that is approved for the treatment of epidermal growth
factor receptor (EGFR) mutation-positive non-small-cell lung cancer (NSCLC). Pivotal …