Genetic rescue: a safe or risky bet?

DM Waller - 2015 - Wiley Online Library
Small and isolated populations face threats from genetic drift and inbreeding. To rescue
populations from these threats, conservation biologists can augment gene flow into small …

Genetic rescue of small inbred populations: Meta‐analysis reveals large and consistent benefits of gene flow

R Frankham - Molecular ecology, 2015 - Wiley Online Library
Many species have fragmented distribution with small isolated populations suffering
inbreeding depression and/or reduced ability to evolve. Without gene flow from another …

What can livestock breeders learn from conservation genetics and vice versa?

TN Kristensen, AA Hoffmann, C Pertoldi… - Frontiers in …, 2015 - frontiersin.org
The management of livestock breeds and threatened natural population share common
challenges, including small effective population sizes, high risk of inbreeding, and the …

Evaluating the outcomes of genetic rescue attempts

ZL Robinson, DA Bell, T Dhendup… - Conservation …, 2021 - Wiley Online Library
Augmenting gene flow is a powerful tool for the conservation of small, isolated populations.
However, genetic rescue attempts have largely been limited to populations at the brink of …

Genomic and fitness consequences of inbreeding in an endangered carnivore

M Hasselgren, N Dussex, J von Seth… - Molecular …, 2021 - Wiley Online Library
Reduced fitness through genetic drift and inbreeding is a major threat to small and isolated
populations. Although previous studies have generally used genetically verified pedigrees …

Genetic rescue: A critique of the evidence supports maximizing genetic diversity rather than minimizing the introduction of putatively harmful genetic variation

K Ralls, P Sunnucks, RC Lacy, R Frankham - Biological Conservation, 2020 - Elsevier
Genetic rescue–ameliorating inbreeding depression and restoring genetic diversity of inbred
populations through gene flow-is valuable in wildlife conservation. Empirically validated …

The exciting potential and remaining uncertainties of genetic rescue

DA Bell, ZL Robinson, WC Funk, SW Fitzpatrick… - Trends in Ecology & …, 2019 - cell.com
Restoring gene flow into small, isolated populations can alleviate genetic load and decrease
extinction risk (ie, genetic rescue), yet gene flow is rarely augmented as a conservation …

Beyond the beneficial effects of translocations as an effective tool for the genetic restoration of isolated populations

JL Bouzat, JA Johnson, JE Toepfer, SA Simpson… - Conservation …, 2009 - Springer
Translocations are becoming increasingly popular as appropriate management strategies
for the genetic restoration of endangered species and populations. Although a few studies …

Inbreeding effects in wild populations

LF Keller, DM Waller - Trends in ecology & evolution, 2002 - cell.com
Whether inbreeding affects the demography and persistence of natural populations has
been questioned. However, new pedigree data from field populations and molecular and …

Genetic decline, restoration and rescue of an isolated ungulate population

MA Poirier, DW Coltman, F Pelletier… - Evolutionary …, 2019 - Wiley Online Library
Isolation of small populations is expected to reduce fitness through inbreeding and loss of
genetic variation, impeding population growth and compromising population persistence …