Chapter 16: Prophylactic human papillomavirus vaccines

DR Lowy, IH Frazer - JNCI Monographs, 2003 - academic.oup.com
Candidate prophylactic vaccines based on papillomavirus L1 virus-like particles (VLPs) are
currently in human clinical trials. The main long-term goal of the vaccine is to reduce the …

A review of clinical trials of human papillomavirus prophylactic vaccines

JT Schiller, X Castellsagué, SM Garland - Vaccine, 2012 - Elsevier
End of study analyses of the phase III trials of prophylactic human papillomavirus (HPV)
virus-like particle (VLP) vaccines in young women are now largely completed. Two distinct …

[HTML][HTML] Suppl 2: therapeutic human papillomavirus (HPV) vaccines: a novel approach

K Kawana, K Adachi, S Kojima, S Kozuma… - The open virology …, 2012 - ncbi.nlm.nih.gov
Cervical cancer is the second largest cause of cancer-related death in women worldwide,
and it occurs following persistent infection, sometimes for decades, with a specific subset of …

Human papillomavirus vaccines

J Schiller, D Lowy, L Markowithz - Vaccines. 6th ed. Philadelphia …, 2012 - books.google.com
Human papilloma virus (HPV) infections, which are common, produce epithelial lesions of
the nongenital and genital skin and mucous membranes. Although most infections are …

A review of prophylactic human papillomavirus vaccines: recommendations and monitoring in the US

EF Dunne, SD Datta, L E. Markowitz - Cancer, 2008 - Wiley Online Library
It has been estimated that genital human papillomavirus (HPV) is the most common sexually
transmitted infection in the US. Nononcogenic types, such as HPV type 6 (HPV‐6) and HPV …

Preventative and therapeutic vaccines for cervical cancer

R Roden, TC Wu - Expert review of vaccines, 2003 - Taylor & Francis
'High-risk'genotypes of the human papillomavirus (HPV), most commonly HPV genotype 16,
are the primary etiologic agents of cervical cancer. Indeed HPV DNA is detected in 99% of …

Prevention strategies against the human papillomavirus: the effectiveness of vaccination

M Stanley - Gynecologic oncology, 2007 - Elsevier
It has been clearly established that sexually transmitted human papillomavirus (HPV)
infections are the major cause of genital warts and cervical cancer and are a contributing …

Vaccines for the prevention of human papillomavirus and associated gynecologic diseases: a review

KA Ault - Obstetrical & gynecological survey, 2006 - journals.lww.com
Routine vaccination programs have had a substantial impact on reducing the prevalence of
a variety of infectious diseases. In light of the fact that human papillomavirus (HPV) is a …

New approaches to prophylactic human papillomavirus vaccines for cervical cancer prevention

ED Gersch, L Gissmann, RL Garcea - Antiviral therapy, 2012 - journals.sagepub.com
The currently licensed human papillomavirus (HPV) vaccines are safe and highly effective at
preventing HPV infection for a select number of papillomavirus types, thus decreasing the …

Introducing human papillomavirus vaccines—questions remain

J Paavonen, M Lehtinen - Annals of Medicine, 2008 - Taylor & Francis
Genital human papillomavirus (HPV) infection and HPV‐associated cervical and other
anogenital cancers are significant public health problems. HPV 16 and HPV 18 are …