EMPOP—a forensic mtDNA database

W Parson, A Dür - Forensic Science International: Genetics, 2007 - Elsevier
Mitochondrial DNA databases stand as the basis for frequency estimations of mtDNA
sequences that became relevant in a case. The establishment of mtDNA databases sounds …

PhyloTree Build 17: Growing the human mitochondrial DNA tree

M Van Oven - Forensic Science International: Genetics Supplement …, 2015 - Elsevier
An accurate, up-to-date, detailed and global phylogenetic tree of human mitochondrial DNA
(mtDNA) is essential for various forensic mtDNA applications including data quality control …

mtDNA variation and analysis using mitomap and mitomaster

MT Lott, JN Leipzig, O Derbeneva… - Current protocols in …, 2013 - Wiley Online Library
The Mitomap database of human mitochondrial DNA (mtDNA) information has been an
important compilation of mtDNA variation for researchers, clinicians, and genetic counselors …

Updating the African human mitochondrial DNA tree: relevance to forensic and population genetics

T Heinz, M Pala, A Gómez-Carballa… - Forensic Science …, 2017 - Elsevier
Abstract Analysis of human mitochondrial DNA (mtDNA) variation plays an important role in
forensic genetic investigations, especially in degraded biological samples and hair shafts …

Evaluation of mitogenome sequence concordance, heteroplasmy detection, and haplogrouping in a worldwide lineage study using the Precision ID mtDNA Whole …

C Strobl, JC Cihlar, R Lagacé, S Wootton… - Forensic Science …, 2019 - Elsevier
Abstract The emergence of Massively Parallel Sequencing technologies enabled the
analysis of full mitochondrial (mt) DNA sequences from forensically relevant samples that …

Recommendations for consistent treatment of length variants in the human mitochondrial DNA control region

MR Wilson, MW Allard, K Monson, KWP Miller… - Forensic science …, 2002 - Elsevier
Human mitochondrial DNA (mtDNA) analysis is a valuable forensic tool, useful in cases
where the amount of extracted DNA is low or highly degraded. Population databases are …

Mitochondrial DNA in human identification: a review

A Amorim, T Fernandes, N Taveira - PeerJ, 2019 - peerj.com
Mitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies,
especially related to the lack of recombination, to a high copy number, and to matrilineal …

Evaluation of GeneMarker® HTS for improved alignment of mtDNA MPS data, haplotype determination, and heteroplasmy assessment

MM Holland, ED Pack, JA McElhoe - Forensic Science International …, 2017 - Elsevier
Existing software has not allowed for effective alignment of mitochondrial (mt) DNA
sequence data generated using a massively parallel sequencing (MPS) approach …

Forensics and mitochondrial DNA: applications, debates, and foundations

B Budowle, MW Allard, MR Wilson… - Annual review of …, 2003 - annualreviews.org
Debate on the validity and reliability of scientific methods often arises in the courtroom.
When the government (ie, the prosecution) is the proponent of evidence, the defense is …

Development and assessment of an optimized next-generation DNA sequencing approach for the mtgenome using the Illumina MiSeq

JA McElhoe, MM Holland, KD Makova, MSW Su… - Forensic Science …, 2014 - Elsevier
The development of molecular tools to detect and report mitochondrial DNA (mtDNA)
heteroplasmy will increase the discrimination potential of the testing method when applied to …