Mechanisms of Parkinson's disease-related proteins in mediating secondary brain damage after cerebral ischemia
TH Kim, R Vemuganti - Journal of Cerebral Blood Flow & …, 2017 - journals.sagepub.com
Both Parkinson's disease (PD) and stroke are debilitating conditions that result in neuronal
death and loss of neurological functions. These two conditions predominantly affect aging …
death and loss of neurological functions. These two conditions predominantly affect aging …
α-Synuclein is a pathological link and therapeutic target for Parkinson's disease and traumatic brain injury
M Shahaduzzaman, S Acosta, PC Bickford… - Medical …, 2013 - Elsevier
Parkinson's disease (PD) affects more than 1% of population over 65 and it is characterized
by gradual loss of nigrostriatal dopaminergic neurons and wide spread accumulation of α …
by gradual loss of nigrostriatal dopaminergic neurons and wide spread accumulation of α …
Molecular mechanism of cognitive impairment associated with Parkinson's disease: A stroke perspective
S Gupta, J Khan, S Ghosh - Life Sciences, 2023 - Elsevier
Parkinson's disease (PD) is a common neurological illness that causes several motor and
non-motor symptoms, most characteristically limb tremors and bradykinesia. PD is a slowly …
non-motor symptoms, most characteristically limb tremors and bradykinesia. PD is a slowly …
Parkin and 𝛂-Synuclein: Opponent Actions in The Pathogenesis of Parkinson'S Disease
MJ Baptista, MR Cookson, DW Miller - The Neuroscientist, 2004 - journals.sagepub.com
Dominant mutations in the gene for•-synuclein, a small presynaptic protein, can cause
Parkinson's disease. Although there is still substantial debate about the precise …
Parkinson's disease. Although there is still substantial debate about the precise …
On the pathogenesis and neuroprotective treatment of Parkinson disease: what have we learned from the genetic forms of this disease?
MA Mena, JA Rodriguez-Navarro, R Ros… - Current medicinal …, 2008 - ingentaconnect.com
Parkinson's disease (PD) is a neurodegenerative disorder affecting nearly 3 million patients
in Europe and North America, characterized by a core phenotype of motor deficits, akinesia …
in Europe and North America, characterized by a core phenotype of motor deficits, akinesia …
Molecular pathways in sporadic PD
EM Valente, G Arena, L Torosantucci… - Parkinsonism & related …, 2012 - Elsevier
Over the last decade, several autosomal dominant and recessive genes causative of
Parkinson's disease (PD) have been identified. The functional studies on their protein …
Parkinson's disease (PD) have been identified. The functional studies on their protein …
New insights on Parkinson's disease genes: the link between mitochondria impairment and neuroinflammation
D Trudler, Y Nash, D Frenkel - Journal of Neural Transmission, 2015 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by
motor disturbances, appearance of Lewy bodies and dopaminergic neuronal death. The …
motor disturbances, appearance of Lewy bodies and dopaminergic neuronal death. The …
Molecular changes in the postmortem parkinsonian brain
D Toulorge, AHV Schapira, R Hajj - Journal of neurochemistry, 2016 - Wiley Online Library
Parkinson disease (PD) is the second most common neurodegenerative disease after
Alzheimer disease. Although PD has a relatively narrow clinical phenotype, it has become …
Alzheimer disease. Although PD has a relatively narrow clinical phenotype, it has become …
Induction of Parkinson disease-related proteins in motor neurons after transient spinal cord ischemia in rabbits
M Sakurai, T Kawamura, H Nishimura… - Journal of Cerebral …, 2009 - journals.sagepub.com
The mechanism of spinal cord injury has been thought to be related to the vulnerability of
spinal motor neuron cells against ischemia. However, the mechanisms of such vulnerability …
spinal motor neuron cells against ischemia. However, the mechanisms of such vulnerability …
α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 …
Parkinson's disease (PD) is a severe neurodegenerative disorder characterised by loss of
dopaminergic neurons of the substantia nigra. The pathological hallmarks are cytoplasmic …
dopaminergic neurons of the substantia nigra. The pathological hallmarks are cytoplasmic …