Recellularization of well-preserved acellular kidney scaffold using embryonic stem cells

B Bonandrini, M Figliuzzi, E Papadimou… - … Engineering Part A, 2014 - liebertpub.com
For chronic kidney diseases, there is little chance that the vast majority of world's population
will have access to renal replacement therapy with dialysis or transplantation. Tissue …

Decellularized kidney matrix as functional material for whole organ tissue engineering

M Figliuzzi, B Bonandrini… - Journal of applied …, 2017 - journals.sagepub.com
Renal transplantation is currently the most effective treatment for end-stage renal disease,
which represents one of the major current public health problems. However, the number of …

[HTML][HTML] The effective bioengineering method of implantation decellularized renal extracellular matrix scaffolds

Y Guan, S Liu, C Sun, G Cheng, F Kong, Y Luan… - Oncotarget, 2015 - ncbi.nlm.nih.gov
End stage renal disease (ESRD) is a progressive loss of kidney function with a high rate of
morbidity and mortality. Transplantable organs are hard to come by and hold a high risk of …

Embryonic stem cells proliferate and differentiate when seeded into kidney scaffolds

EA Ross, MJ Williams, T Hamazaki… - Journal of the …, 2009 - journals.lww.com
The scarcity of transplant allografts for diseased organs has prompted efforts at tissue
regeneration using seeded scaffolds, an approach hampered by the enormity of cell types …

Repopulation of porcine kidney scaffold using porcine primary renal cells

M Abolbashari, SM Agcaoili, MK Lee, IK Ko… - Acta biomaterialia, 2016 - Elsevier
The only definitive treatment for end stage renal disease is renal transplantation, however
the current shortage of organ donors has resulted in a long list of patients awaiting …

Biocompatibility and hemocompatibility of efficiently decellularized whole porcine kidney for tissue engineering

KH Hussein, T Saleh, E Ahmed… - … Research Part A, 2018 - Wiley Online Library
Whole kidney decellularization is a promising approach in regenerative medicine for
engineering a functional organ. The reaction of the potential host depends on the …

Decellularized rhesus monkey kidney as a three-dimensional scaffold for renal tissue engineering

KH Nakayama, CA Batchelder, CI Lee… - … Engineering Part A, 2010 - liebertpub.com
The goal of this study was the production of a decellularized kidney scaffold with structural,
mechanical, and physiological properties necessary for engineering basic renal structures in …

Experimental evaluation of kidney regeneration by organ scaffold recellularization

A Remuzzi, M Figliuzzi, B Bonandrini, S Silvani… - Scientific reports, 2017 - nature.com
The rising number of patients needing renal replacement therapy, alongside the significant
clinical and economic limitations of current therapies, creates an imperative need for new …

Decellularized kidney scaffold-mediated renal regeneration

YL Yu, YK Shao, YQ Ding, KZ Lin, B Chen, HZ Zhang… - Biomaterials, 2014 - Elsevier
Renal regeneration approaches offer great potential for the treatment of chronic kidney
disease, but their availability remains limited by the clinical challenges they pose. In the …

Renal tissue engineering with decellularized rhesus monkey kidneys: age-related differences

KH Nakayama, CA Batchelder, CI Lee… - … Engineering Part A, 2011 - liebertpub.com
New therapies for severely damaged kidneys are needed due to limited regenerative
capacity and organ donor shortages. The goal of this study was to repopulate decellularized …