The integrin family of transmembrane adhesion receptors is essential for sensing and
adhering to the extracellular environment. Integrins are heterodimers composed of non …

In their roles as major adhesion receptors, integrins signal across the plasma membrane in
both directions. Recent structural and cell biological data suggest models for how integrins …

Integrin signaling is bidirectional.'Inside-out'signals regulate integrin affinity for adhesive
ligands, and ligand-dependent 'outside-in'signals regulate cellular responses to adhesion …

Integrins are large, membrane-spanning, heterodimeric proteins that are essential for a
metazoan existence. All members of the integrin family adopt a shape that resembles a large …

Integrins are heterodimeric transmembrane adhesion receptors that couple the actin
cytoskeleton to the extracellular environment and bidirectionally relay signals across the cell …

Integrins are αβ heterodimeric adhesion receptors that relay signals bidirectionally across
the plasma membrane between the extracellular matrix and cell-surface ligands, and …

Integrins receive signals from other receptors that lead to activation of ligand binding (inside-
out signaling) and matrix assembly. Upon binding ligands, they also activate intracellular …

Integrins are cell adhesion molecules that mediate cell-cell, cell–extracellular matrix, and
cell-pathogen interactions. They play critical roles for the immune system in leukocyte …

Integrins are heterodimeric cell surface adhesion receptors essential for multicellular life.
They connect cells to the extracellular environment and transduce chemical and mechanical …

Integrins are cell surface adhesion receptors that are essential for the development and
function of multicellular animals. Here we summarize recent findings on the regulation of …