New insights into the structural basis of integrin activation
JP Xiong, T Stehle, SL Goodman, MA Arnaout - Blood, 2003 - ashpublications.org
Integrins are cell adhesion receptors that communicate biochemical and mechanical signals
in a bidirectional manner across the plasma membrane and thus influence most cellular …
in a bidirectional manner across the plasma membrane and thus influence most cellular …
Regulation of integrin activation
Regulation of cell-cell and cell-matrix interaction is essential for the normal physiology of
metazoans and is important in many diseases. Integrin adhesion receptors can rapidly …
metazoans and is important in many diseases. Integrin adhesion receptors can rapidly …
Research advances on structure and biological functions of integrins
L Pan, Y Zhao, Z Yuan, G Qin - Springerplus, 2016 - Springer
Integrins are an important family of adhesion molecules that were first discovered two
decades ago. Integrins are transmembrane heterodimeric glycoprotein receptors consisting …
decades ago. Integrins are transmembrane heterodimeric glycoprotein receptors consisting …
Integrins: emerging paradigms of signal transduction.
MA Schwartz, MD Schaller… - Annual review of cell and …, 1995 - europepmc.org
Integrins receive signals from other receptors that lead to activation of ligand binding (inside-
out signaling) and matrix assembly. Upon binding ligands, they also activate intracellular …
out signaling) and matrix assembly. Upon binding ligands, they also activate intracellular …
Integrin structure
MJ Humphries - Biochemical Society Transactions, 2000 - portlandpress.com
The integrins are a family of α, β heterodimeric receptors that mediate dynamic linkages
between extracellular adhesion molecules and the intracellular actin cytoskeleton. Integrins …
between extracellular adhesion molecules and the intracellular actin cytoskeleton. Integrins …
Integrins and signal transduction
S Dedhar - Current opinion in hematology, 1999 - journals.lww.com
Integrins are dynamic cell-surface receptors that provide a physical link between the
extracellular matrix and the cell cytoskeleton. The interaction of integrins with extracellular …
extracellular matrix and the cell cytoskeleton. The interaction of integrins with extracellular …
Integrin structure and function
MB Srichai, R Zent - Cell-extracellular matrix interactions in cancer, 2010 - Springer
Integrins are a large family of heterodimeric glycoprotein receptors first discovered over
twenty years ago. They exist as two noncovalently bound a-and b-subunits that function as …
twenty years ago. They exist as two noncovalently bound a-and b-subunits that function as …
Integrin-mediated signal transduction
CM Longhurst, LK Jennings - Cellular and Molecular Life Sciences CMLS, 1998 - Springer
Integrins, expressed on virtually every cell type, are proteins that mediate cellular
interactions with components of the extracellular matrix (ECM) and cell surface integral …
interactions with components of the extracellular matrix (ECM) and cell surface integral …
Integrin activation: the link between ligand binding and signal transduction
MJ Humphries - Current opinion in cell biology, 1996 - Elsevier
A major function of the integrin family of receptors is to provide a physical connection
between extracellular adhesion proteins and intracellular cytoskeletal/signalling molecules …
between extracellular adhesion proteins and intracellular cytoskeletal/signalling molecules …
Mechanisms of integrin activation and trafficking
C Margadant, HN Monsuur, JC Norman… - Current opinion in cell …, 2011 - Elsevier
Integrin adhesion receptors are essential for the normal function of most multicellular
organisms, and defective integrin activation or integrin signaling is associated with an array …
organisms, and defective integrin activation or integrin signaling is associated with an array …