[HTML][HTML] EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma
L Yang, L Liu, Z Xu, W Liao, D Feng, X Dong, S Xu… - Oncotarget, 2015 - ncbi.nlm.nih.gov
LMP1, which is encoded by the Epstein-Barr virus, is proposed to be one of the major
oncogenic factors involved in nasopharyngeal carcinoma (NPC). Previous studies …
oncogenic factors involved in nasopharyngeal carcinoma (NPC). Previous studies …
Targeting EBV-LMP1 DNAzyme enhances radiosensitivity of nasopharyngeal carcinoma cells by inhibiting telomerase activity
L Yang, Z Xu, L Liu, X Luo, J Lu, L Sun… - Cancer biology & …, 2014 - Taylor & Francis
The latent membrane protein 1 (LMP1), which is encoded by the Epstein–Barr virus (EBV),
has been suggested to be one of the major oncogenic factors in nasopharyngeal carcinoma …
has been suggested to be one of the major oncogenic factors in nasopharyngeal carcinoma …
[PDF][PDF] Epstein-Barr virus-encoded LMP1 increases miR-155 expression, which promotes radioresistance of nasopharyngeal carcinoma via suppressing UBQLN1.
F Yang, Q Liu, CM Hu - European Review for Medical & …, 2015 - europeanreview.org
OBJECTIVE: Epstein-Barr virus (EBV)-encoded latent membrane protein (LMP1) can drive
aberrant expression of miR-155 in nasopharyngeal carcinoma (NPC). In this study, we …
aberrant expression of miR-155 in nasopharyngeal carcinoma (NPC). In this study, we …
[HTML][HTML] A therapeutic approach to nasopharyngeal carcinomas by DNAzymes targeting EBV LMP-1 gene
L Yang, Z Lu, X Ma, Y Cao, LQ Sun - Molecules, 2010 - mdpi.com
Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) has been known to
have oncogenic properties during latent infection in nasopharyngeal carcinoma (NPC) …
have oncogenic properties during latent infection in nasopharyngeal carcinoma (NPC) …
EBV-LMP1-targeted DNAzyme restrains nasopharyngeal carcinoma growth in a mouse C666-1 xenograft model
X Ke, Y Yang, S Hong - Medical oncology, 2011 - Springer
Abstract Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) has been
demonstrated to be linked to the pathogenesis of nasopharyngeal carcinoma (NPC), one of …
demonstrated to be linked to the pathogenesis of nasopharyngeal carcinoma (NPC), one of …
[HTML][HTML] EBV-LMP1-targeted DNAzyme induces DNA damage and causes cell cycle arrest in LMP1-positive nasopharyngeal carcinoma cells
X Ma, Z Xu, L Yang, L Xiao… - International …, 2013 - spandidos-publications.com
This study aimed to determine the molecular mechanisms underlying the effect of the LMP1-
targeted DNAzyme 1 (DZ1) on cell cycle progression in nasopharyngeal carcinoma (NPC) …
targeted DNAzyme 1 (DZ1) on cell cycle progression in nasopharyngeal carcinoma (NPC) …
Cancer stem-like cell characteristics induced by EB virus-encoded LMP1 contribute to radioresistance in nasopharyngeal carcinoma by suppressing the p53-mediated …
CF Yang, LX Peng, TJ Huang, GD Yang, QQ Chu… - Cancer letters, 2014 - Elsevier
Emerging evidence confirms that cancer stem cells (CSCs) are responsible for the
chemoradioresistance of malignancies. EBV-encoded latent membrane protein 1 (LMP1) is …
chemoradioresistance of malignancies. EBV-encoded latent membrane protein 1 (LMP1) is …
DNAzymes targeted to EBV-encoded latent membrane protein-1 induce apoptosis and enhance radiosensitivity in nasopharyngeal carcinoma
ZX Lu, XQ Ma, LF Yang, ZL Wang, L Zeng, ZJ Li, XN Li… - Cancer letters, 2008 - Elsevier
Epstein-Barr virus (EBV) is involved in the carcinogenesis of several types of cancers such
as nasopharyngeal carcinoma (NPC) and Burkitt's lymphoma. The latent membrane protein …
as nasopharyngeal carcinoma (NPC) and Burkitt's lymphoma. The latent membrane protein …
[HTML][HTML] Down-regulation of EBV-LMP1 radio-sensitizes nasal pharyngeal carcinoma cells via NF-κB regulated ATM expression
X Ma, L Yang, L Xiao, M Tang, L Liu, Z Li, M Deng… - PLoS …, 2011 - journals.plos.org
Background The latent membrane protein 1 (LMP1) encoded by EBV is expressed in the
majority of EBV-associated human malignancies and has been suggested to be one of the …
majority of EBV-associated human malignancies and has been suggested to be one of the …
EBV-LMP1 suppresses the DNA damage response through DNA-PK/AMPK signaling to promote radioresistance in nasopharyngeal carcinoma
J Lu, M Tang, H Li, Z Xu, X Weng, J Li, X Yu, L Zhao… - Cancer letters, 2016 - Elsevier
We conducted this research to explore the role of latent membrane protein 1 (LMP1)
encoded by the Epstein–Barr virus (EBV) in modulating the DNA damage response (DDR) …
encoded by the Epstein–Barr virus (EBV) in modulating the DNA damage response (DDR) …
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