Prothrombotic antiphospholipid antibodies in COVID-19

Y Zuo, SK Estes, RA Ali, AA Gandhi, S Yalavarthi, H Shi… - MedRxiv, 2020 - medrxiv.org
Patients with coronavirus disease 19 (COVID-19) are at high risk for thrombotic arterial and
venous occlusions. At the same time, lung histopathology often reveals fibrin-based …

Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19

Y Zuo, SK Estes, RA Ali, AA Gandhi… - Science translational …, 2020 - science.org
Patients with COVID-19 are at high risk for thrombotic arterial and venous occlusions. Lung
histopathology often reveals fibrin-based blockages in the small blood vessels of patients …

[HTML][HTML] Anti-phospholipid antibodies in COVID-19 are different from those detectable in the anti-phospholipid syndrome

MO Borghi, A Beltagy, E Garrafa, D Curreli… - Frontiers in …, 2020 - frontiersin.org
Background Critically ill patients with coronavirus disease 2019 (COVID-19) have a
profound hypercoagulable state and often develop coagulopathy which leads to organ …

[HTML][HTML] Outcomes associated with antiphospholipid antibodies in COVID-19: A prospective cohort study

A Mendel, MJ Fritzler, Y St-Pierre, J Rauch… - Research and Practice …, 2023 - Elsevier
Background The significance of antiphospholipid antibodies (aPL) in COVID-19 remains
uncertain. Objectives We determined whether aPL are associated with COVID-19 and/or …

COVID-19 and antiphospholipid antibodies: time for a reality check?

EJ Favaloro, BM Henry, G Lippi - Seminars in Thrombosis and …, 2022 - thieme-connect.com
Antiphospholipid antibodies (aPL) comprise a panel of autoantibodies that reflect a potential
prothrombotic risk in several autoimmune conditions, most notably antiphospholipid …

Prevalence, specificity and clinical association of anti-phospholipid antibodies in COVID-19 patients: are the antibodies really guilty?

MO Borghi, A Beltagy, E Garrafa, D Curreli, G Cecchini… - MedRxiv, 2020 - medrxiv.org
Background Critically ill patients with coronavirus disease 2019 (COVID-19) have a
profound hypercoagulable state and often develop coagulopathy which leads to organ …

Anti-phospholipid antibodies and COVID-19 thrombosis: a co-star, not a supporting actor

FJ Gil-Etayo, S Garcinuño, A Lalueza, R Díaz-Simón… - Biomedicines, 2021 - mdpi.com
Background: COVID-19 clinical features include a hypercoagulable state that resembles the
antiphospholipid syndrome (APS), a disease characterized by thrombosis and presence of …

[HTML][HTML] Pathogenic lipid‐binding antiphospholipid antibodies are associated with severity of COVID‐19

A Hollerbach, N Müller‐Calleja, D Pedrosa… - Journal of Thrombosis …, 2021 - Elsevier
Abstract Background Coronavirus disease 19 (COVID‐19)–associated coagulopathy is a
hallmark of disease severity and poor prognosis. The key manifestations of this …

[HTML][HTML] Autoantibodies in COVID-19: frequency and function

Z Gao, H Zhang, C Liu, KE Dong - Autoimmunity Reviews, 2021 - ncbi.nlm.nih.gov
COVID-19 pandemic that induced by SARS-CoV-2 has been going on for more than ten
months, and shows no sign of abating. Numerous COVID-19 cohort studies have been …

Persistent antiphospholipid antibodies are not associated with worse clinical outcomes in a prospective cohort of hospitalised patients with SARS-CoV-2 infection

G Espinosa, C Zamora-Martínez… - Frontiers in …, 2022 - frontiersin.org
Objective Patients with COVID-19 presented with an elevated prevalence of
antiphospholipid antibodies (aPL) but the relationship with thrombosis is controversial. We …