Inducible costimulator (ICOS) expression is critical for T cell-mediated immunity. We showed
previously that T cell receptor and CD28 coengagement up-regulate ICOS expression in …

The inducible costimulator (ICOS), a member of the CD28 family of costimulatory molecules,
is rapidly induced upon T cell activation. Although the critical role of ICOS in costimulating T …

Helper T (Th) cell differentiation is accompanied by complex transcriptional changes.
Although costimulatory receptors are important in Th differentiation, the underlying …

The CD28 homologue inducible costimulator (ICOS) has been demonstrated to regulate a
number of T cell‐dependent immune responses in vivo. However, the expression and …

The inducible costimulatory (ICOS) molecule is expressed by activated T cells and has
homology to CD28 and CD152. ICOS binds B7h, a molecule expressed by APC with …

Inducible costimulator (ICOS) is a new member of the CD28/CTLA-4 family that is expressed
on activated and germinal center (GC) T cells. Recently, we reported that ICOS-deficient …

The inducible costimulator (ICOS) is highly expressed in follicular helper T (Tfh) cells, a
subset of CD4 T cells that migrate into the B cell zone and facilitate germinal center …

The Inducible Costimulator molecule (ICOS), a member of the CD28 family of costimulatory
molecules, was identified in 1999 as a molecule expressed primarily on activated human T …

The inducible costimulator (ICOS) is a T cell costimulatory receptor that plays crucial roles in
T cell differentiation and function. So far, ICOS has been shown to activate three signaling …

Activated in immune responses, T lymphocytes differentiate into effector cells with potent
immune function. CD28 is the most prominent costimulatory receptor for T‐cell activation …