Emerging significance and therapeutic targets of ferroptosis: a potential avenue for human kidney diseases

J Li, S Zheng, Y Fan, K Tan - Cell Death & Disease, 2023 - nature.com
Kidney diseases remain one of the leading causes of human death and have placed a
heavy burden on the medical system. Regulated cell death contributes to the pathology of a …

Ferroptosis and acute kidney injury (AKI): molecular mechanisms and therapeutic potentials

Q Feng, X Yu, Y Qiao, S Pan, R Wang… - Frontiers in …, 2022 - frontiersin.org
Acute kidney injury (AKI), a common and serious clinical kidney syndrome with high
incidence and mortality, is caused by multiple pathogenic factors, such as ischemia …

Novel insight into ferroptosis in kidney diseases

L Yang, Y Liu, S Zhou, Q Feng, Y Lu, D Liu… - American Journal of …, 2023 - karger.com
Background: Various kidney diseases such as acute kidney injury, chronic kidney disease,
polycystic kidney disease, renal cancer, and kidney stones, are an important part of the …

[HTML][HTML] Broadening horizons: the multifaceted functions of ferroptosis in kidney diseases

Q Feng, Y Yang, K Ren, Y Qiao, Z Sun… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Ferroptosis is an iron-dependent programmed cell death pattern that is characterized by iron
overload, reactive oxygen species (ROS) accumulation and lipid peroxidation. Growing …

The role of ferroptosis in the development of acute and chronic kidney diseases

Y Zhou, J Zhang, Q Guan, X Tao… - Journal of cellular …, 2022 - Wiley Online Library
Ferroptosis, a novel form of regulated cell death, is characterized by imbalance of
intracellular iron and redox systems, resulting from overgeneration of toxic lipid peroxidation …

Abnormal iron and lipid metabolism mediated ferroptosis in kidney diseases and its therapeutic potential

X Zhang, X Li - Metabolites, 2022 - mdpi.com
Ferroptosis is a newly identified form of regulated cell death driven by iron-dependent
phospholipid peroxidation and oxidative stress. Ferroptosis has distinct biological and …

Ferroptosis and kidney diseases

S Tang, X Xiao - International Urology and Nephrology, 2020 - Springer
Ferroptosis is a form of iron-dependent, non-apoptotic regulated cell death, which is
characterized by the accumulation of lipid hydroperoxides to lethal levels. Ferroptosis …

The multifaceted role of ferroptosis in kidney diseases

Y Lin, W Xu, Y Hou, S Wang, H Zhang, M Ran… - Chemico-Biological …, 2022 - Elsevier
Ferroptosis, a form of cell death caused by the excessive accumulation of iron-dependent
lipid peroxides. Studies over the last decade have identified multiple pathways that affect the …

The cross‐link between ferroptosis and kidney diseases

J Wang, Y Liu, Y Wang, L Sun - Oxidative Medicine and …, 2021 - Wiley Online Library
Acute and chronic kidney injuries result from structural dysfunction and metabolic disorders
of the kidney in various etiologies, which significantly affect human survival and social …

Targeting ferroptosis in acute kidney injury

L Ni, C Yuan, X Wu - Cell Death & Disease, 2022 - nature.com
Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …