To determine the effects of long-term pressure overload on the structural mechanisms
implicated in wall remodeling of the right ventricle, a mild pulmonary artery banding was …

To determine whether the hypertrophic response of the surviving myocardium after infarction
leads to normalization of ventricular hemodynamics and wall stress, the left coronary artery …

Increased microtubule density causes cardiocyte contractile dysfunction in right ventricular
(RV) pressure-overload hypertrophy, and these linked phenotypic and contractile …

Pressure overload of cat right ventricle causes progressive abnormalities of in vitro
contractile function at a time when in vivo contractile function is normal. In marked contrast …

Introduction normal, the distributions of local stress components may be altered, particularly
the transmural gra-Cardiac hypertrophy is thought to be an adaptive response to altered …

A chronic pressure overload animal model was created in young guinea pigs by surgical
constriction of the descending thoracic aorta. Hemodynamics, echocardiography and …

Light and electron microscopy, combined with morphometry, were utilized to study
myocardial cell modifications induced by a temporary abdominal aortic constriction in the rat …

To determine whether acute left ventricular failure associated with myocardial infarction
leads to architectural changes in the spared nonischemic portion of the ventricular wall …

In contrast to observations made in the human heart, hyperplasia of myocyte nuclei has
never been demonstrated in experimental cardiac hypertrophy. To test the hypothesis that …

We have shown that excess growth hormone (GH) causes left ventricular hypertrophy in rats.
To further characterize cell growth of this model, combined light and electron microscopic …