Adequate local control in high-risk soft tissue sarcoma of the extremity treated with surgery alone at a reference centre: should radiotherapy still be a standard?

M Fiore, S Ford, D Callegaro, C Sangalli… - Annals of surgical …, 2018 - Springer
Background Established practice for the management of soft tissue sarcoma (STS) of the
extremity and trunk wall combines perioperative radiotherapy (RT) with limb-preserving …

Combining limb-sparing surgery with radiation therapy in high-grade soft tissue sarcoma of extremities–Is it effective?

DA Müller, G Beltrami, G Scoccianti, F Frenos… - European Journal of …, 2016 - Elsevier
Background Limb-sparing surgery in combination with radiation therapy is a well-
established treatment for high-grade soft tissue sarcomas of the extremities. But selection of …

Long-term outcomes after function-sparing surgery without radiotherapy for soft tissue sarcoma of the extremities and trunk

EH Baldini, J Goldberg, C Jenner, JB Manola… - Journal of Clinical …, 1999 - ascopubs.org
PURPOSE: To define the rate of local recurrence (LR) and identify prognostic factors for LR
for patients with soft tissue sarcoma (STS) treated with function-sparing surgery (FSS) …

Radiation therapy for extremity soft tissue sarcoma: in the absence of a clear survival benefit, why do we give it?

EH Baldini, C Raut - Annals of Surgical Oncology, 2014 - Springer
Due in large part to several sentinel contributions from the National Cancer Institute (NCI),
the local management of extremity soft tissue sarcoma (ESTS) today typically results in …

Does adjuvant radiation therapy increase loco-regional control after optimal resection of soft-tissue sarcoma of the extremities?

K Khanfir, L Alzieu, P Terrier, C Le Péchoux… - European journal of …, 2003 - Elsevier
Adjuvant radiotherapy (RT) is routinely recommended for most soft-tissue sarcomas (STS) of
the extremities. However, its impact on local control is not clearly established after wide …

The role of neoadjuvant radiochemotherapy in the management of localized high-grade soft tissue sarcoma

M Kobus, S Roohani, F Ehret, A Flörcken, JK Striefler… - Radiation …, 2022 - Springer
Background Standard treatment of soft tissue sarcoma (STS) of the extremities includes limb-
sparing surgery combined with pre-or postoperative radiotherapy (RT). The role of …

Impact of postoperative radiation on survival for high-grade soft tissue sarcoma of the extremities after limb sparing radical resection

D Schreiber, J Rineer, E Katsoulakis… - American Journal of …, 2012 - journals.lww.com
Objectives To use the Surveillance, Epidemiology, and End Results (SEER) Database to
analyze the impact of postoperative radiation after limb sparing surgery for high-grade …

Extremity soft tissue sarcoma: role of local control

EJ Brinkmann, SK Ahmed, MT Houdek - Current Treatment Options in …, 2020 - Springer
Opinion statement For localized extremity soft tissue sarcoma (eSTS), treatment is
individualized and each patient needs to be evaluated by a multidisciplinary team at a …

The risk of postoperative complications and functional impairment after multimodality treatment for limb and trunk wall soft-tissue sarcoma: Long term results from a …

E Stoeckle, A Michot, L Rigal, F Babre, P Sargos… - European Journal of …, 2017 - Elsevier
Background and objectives Conservative surgery for soft-tissue sarcoma (STS) within
multimodality treatment attempts to reconcile two contradictory requirements: assuring a …

The use of radiation therapy in localized high-grade soft tissue sarcoma and potential impact on survival

CH Hou, AL Lazarides, PJ Speicher… - Annals of surgical …, 2015 - Springer
Background It is a consensus that radiation therapy (RT) should be applied for all large,
deep, high-grade soft tissue sarcomas (STS). Therefore, we investigated the National …