Insulin is a critical hormone that promotes energy storage in various tissues, as well as
anabolic functions. Insulin resistance significantly reduces these responses, resulting in …

Insulin is a paramount anabolic hormone that promotes energy-storage in adipose tissue,
skeletal muscle and liver, and these responses are significantly attenuated in insulin …

The prevalence of obesity is increasing rapidly and is closely associated with a variety of
metabolic diseases. Recent studies have suggested that autophagy is likely to play an …

Diabetes mellitus (DM) is an endocrine disorder. In coming decades it will be one of the
leading causes of death globally. The key factors in the pathogenesis of diabetes are …

Autophagy plays an important role in the regulation of cellular homeostasis through
elimination of aggregated proteins, damaged organelles, and intracellular pathogens …

Autophagy, a stress-induced lysosomal degradative pathway, has been assumed to exert
similar metabolic effects in different organs. Here, we establish a model where autophagy …

Autophagy, a double-edged sword for cell survival, is the research object on 2016 Nobel
Prize in Physiology or Medicine. Autophagy is a molecular mechanism for maintaining …

Autophagy functions to degrade and recycle intracellular proteins and damaged organelles,
maintaining the normal cellular function. Autophagy has been shown to play an important …

Dysregulation of autophagy contributes to aging and to diseases such as
neurodegeneration, cardiomyopathy, and cancer. The paper by Yang et al.(2010) in this …

Autophagy is an evolutionarily conserved, lysosome-dependent catabolic process whereby
cytoplasmic components, including damaged organelles, protein aggregates and lipid …