There is convincing evidence that abnormalities of regional brain function exist in
Parkinson's disease (PD). However, many resting-state functional magnetic resonance …

Objective Parkinson's disease (PD) affects the structural integrity and neurophysiological
signaling of the cortex. These alterations are related to the motor and cognitive symptoms of …

HIGHLIGHTS Eighteen EOPD, 21 LOPD and 37 age-matched normal control subjects
participated in the resting state fMRI scans. Age at onset of PD modulates the distribution of …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by a wide array of
motor and non-motor symptoms. It remains unclear whether neurodegeneration in discrete …

Although cardinal motor symptoms in Parkinson's disease (PD) are attributed to dysfunction
of corticostriatal loops, early clinical nonmotor features are more likely to be associated with …

Disturbances in intrinsic activity during resting-state functional MRI (rsfMRI) are common in
Parkinson's disease (PD), but have largely been studied in a priori defined subnetworks …

Resting-state functional magnetic resonance imaging (RS-fMRI) studies have been
extensively applied to analyze the pathophysiology of neurodegenerative disorders such as …

Background. Abnormalities in white matter integrity and specific functional network
alterations have been increasingly reported in patients with Parkinson's disease (PD) …

Background Parkinson's disease (PD) is a common neurodegenerative disorder associated
with gray matter atrophy. Cortical atrophy patterns may further help distinguish between PD …

Objective This study aimed to investigate the differences in regional homogeneity (ReHo)
values in patients with Parkinson's disease (PD) with cognitive impairment (PD-CI) and thus …