Since last two decades, the major cancer research has focused on understanding the
characteristic properties and mechanism of formation of Cancer stem cells (CSCs), due to …

A frequent observation in several malignancies is the development of resistance to therapy
that results in frequent tumor relapse and metastasis. Much of the tumor resistance …

Abstract Background Cancer stem cells (CSCs) are subpopulations of cancer cells sharing
similar characteristics as normal stem or progenitor cells such as self-renewal ability and …

Cancer is recognized as a preeminent factor of the world's mortality. Although various
modalities have been designed to cure this life-threatening ailment, a significant impediment …

The term “cancer stem cells”(CSCs) refers to cancer cells that exhibit traits parallel to normal
stem cells, namely the potential to give rise to every type of cell identified in a tumor …

Current evidence indicates that a subpopulation of cancer cells, named cancer stem cells
(CSCs) or tumor-initiating cells, are responsible for the initiation, growth, metastasis, therapy …

Cancer stem cells (CSCs) comprise the subpopulation of tumor bulk and acquire resistant to
conventional therapies and are considered as the primary tumor initiator cells. Nowadays …

Chemoresistance is a major problem in cancer therapy as cancer cells develop mechanisms
that counteract the effect of chemotherapeutic compounds, leading to relapse and the …

Cancer is a multifactor and multistep process that is affected intrinsically by the genetic and
epigenetic makeup of tumor cells and extrinsically by the host microenvironment and …

Cancer stem cells (CSCs) are a tumour subpopulation whose capacity for self-renewal,
differentiation and proliferation generates unfavourable patient outcomes, including …