Apoptosis in human disease: a new skin for the old ceremony?

B Fadeel, S Orrenius, B Zhivotovsky - Biochemical and biophysical …, 1999 - Elsevier
Naturally occurring cell death or apoptosis is essential for the maintenance of tissue
homeostasis and serves to remove extraneous or dangerous cells in a swift and unobtrusive …

Apoptosis—molecular mechanisms and biomedical implications

DJ McConkey, B Zhivotovsky, S Orrenius - Molecular aspects of medicine, 1996 - Elsevier
Apoptosis is a distinct form of cell death of importance in tissue development and
homeostasis and in several diseases. This review summarizes current knowledge about the …

[HTML][HTML] Role of apoptosis in disease

B Favaloro, N Allocati, V Graziano, C Di Ilio… - Aging (Albany …, 2012 - ncbi.nlm.nih.gov
Since the initial description of apoptosis, a number of different forms of cell death have been
described. In this review we will focus on classic caspase-dependent apoptosis and its …

Apoptosis: an overview of the process and its relevance in disease

SJ Webb, DJ Harrison, AH Wyllie - Advances in pharmacology, 1997 - Elsevier
Publisher Summary This chapter provides an overview of several recent advances in the
study of apoptosis, integrating the molecular events with the physiological and …

Apoptosis: a review of programmed cell death

S Elmore - Toxicologic pathology, 2007 - journals.sagepub.com
The process of programmed cell death, or apoptosis, is generally characterized by distinct
morphological characteristics and energy-dependent biochemical mechanisms. Apoptosis is …

Molecular and clinical aspects of apoptosis

AG Uren, DL Vaux - Pharmacology & therapeutics, 1996 - Elsevier
Unwanted cells are removed by physiological cell death processes that are highly
conserved throughout the animal kingdom. Physiological cell death plays an important role …

Genealogy, expression, and molecular mechanisms in apoptosis

Z Dlamini, Z Mbita, M Zungu - Pharmacology & therapeutics, 2004 - Elsevier
Apoptosis, known as programmed cell death, is a conserved, gene-directed mechanism for
the elimination of unnecessary or unwanted cells from an organism. A retrospective look at …

[HTML][HTML] Cell death pathology: perspective for human diseases

M Agostini, P Tucci, G Melino - Biochemical and biophysical research …, 2011 - Elsevier
Apoptosis, a genetically regulated form of cell death with distinct biochemical and
morphological features, plays a relevant physiological and pathological role in the organism …

[HTML][HTML] Demystified…: apoptosis

S Afford, S Randhawa - Molecular pathology, 2000 - ncbi.nlm.nih.gov
Apoptosis is the genetically regulated form of cell death that permits the safe disposal of
cells at the point in time when they have fulfilled their intended biological function. Examples …

Apoptosis: molecular mechanisms and implications for human disease

S ORRENIUS - Journal of internal medicine, 1995 - Wiley Online Library
Apoptosis is a highly regulated process of cell death with characteristic morphological
changes that are distinct from necrosis. The biochemical machinery responsible for …