Mycobacterium kansasii has emerged as an important nontuberculous mycobacterium
pathogen, whose incidence and prevalence have been increasing in the last decade. M …

The development of effective innate and subsequent adaptive host immune responses is
highly dependent on the production of proinflammatory cytokines that increase the activity of …

Mycobacterium tuberculosis (Mtb) has evolved to evade host innate immunity by interfering
with macrophage functions. Interleukin-1β (IL-1β) is secreted by macrophages after the …

As a hallmark of tuberculosis (TB), Mycobacterium tuberculosis (MTB) induces
granulomatous lung lesions and systemic inflammatory responses during active disease …

Mycoplasma pneumoniae is an atypical bacterial respiratory pathogen known to cause a
range of airway inflammation and lung and extrapulmonary pathologies. We recently …

Mycobacterium tuberculosis (MTB) infection is characterized by granulomatous lung lesions
and systemic inflammatory responses during active disease. Inflammasome activation is …

The incidence of nontuberculous mycobacteria lung disease (NTM-LD) is increasing in
patients without human immunodeficiency virus. Mycobacterium avium complex (MAC) is …

Pathogenic mycobacteria, such as Mycobacterium tuberculosis, Mycobacterium bovis, and
Mycobacterium marinum, can trigger NLRP3 inflammasome activation leading to maturation …

The production of IL-1β during the infection with Mycobacterium tuberculosis (Mtb) is
important for successful host immune defense. In macrophages and dendritic cells the host …

Mycobacterium bovis is the causative agent of tuberculosis in a wide range of mammals,
including humans. Macrophages are the first line of host defense. They secrete …